USA flag logo/image

An Official Website of the United States Government

Company Information:

Company Name:
ORTHOSYSTEMS, INC.
Address:
100 Intrepid Lane
Suite 1
Syracuse, NY 13205-
Phone:
N/A
URL:
N/A
EIN:
841618920
DUNS:
138843722
Number of Employees:
N/A
Woman-Owned?:
No
Minority-Owned?:
No
HUBZone-Owned?:
No

Commercialization:

Has been acquired/merged with?:
N/A
Has had Spin-off?:
N/A
Has Had IPO?:
N/A
Year of IPO:
N/A
Has Patents?:
N/A
Number of Patents:
N/A
Total Sales to Date $:
$ 0.00
Total Investment to Date $
$ 0.00
POC Title:
N/A
POC Name:
N/A
POC Phone:
N/A
POC Email:
N/A
Narrative:
N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $602,120.00 4
SBIR Phase II $2,561,009.00 2
STTR Phase I $199,967.00 2
STTR Phase II $751,587.00 1

Award List:

OrthoSwith Probes for High Throughput Screening

Award Year / Program / Phase:
2004 / STTR / Phase II
Award Amount:
$751,587.00
Agency:
HHS
Principal Investigator:
Research Institution:
SYRACUSE UNIVERSITY
RI Contact:
N/A
Abstract:
DESCRIPTION (provided by applicant): This project aims at creating and using the tools to screen large libraries of chemical compounds to find and evaluate drug candidates for three targets in HIV-1. These are (1) the RNAnucleocapsid (NC) protein complex, (2) the TAR RNA-Tat protein-CyclinT1 protein… More

Detecting Ricin with Engineered Sensor Switches

Award Year / Program / Phase:
2004 / SBIR / Phase I
Award Amount:
$99,981.00
Agency:
DHS
Principal Investigator:
Mark P. McPike, Chief Scientific Officer
Abstract:
OrthoSystems, Inc. creates switchable molecular sensors for bioterror agents and other targets. In this project our OrthoSwitchTM technology platform will be used to develop a rapid diagnostic device for detecting ricin in solution. OrthoSwitchesTM are custom designed molecular sensors that function… More

Microarray chips for rapid detection of high affinity nucleic acid sequences

Award Year / Program / Phase:
2006 / SBIR / Phase I
Award Amount:
$112,494.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): This phase I project aims at demonstrating a method to rapidly discover short sequences that bind tightly to protein targets. Our plan in phase I is limited to proof of principle by screening against fluorescently tagged proteins, which will facilitate analysis.… More

Microarray Chips for Rapid Detection of High Affinity Nucleic Acid Sequences.

Award Year / Program / Phase:
2008 / SBIR / Phase II
Award Amount:
$973,455.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): This Phase II project aims at further advancing and commercializing a microarray-based screening approach, for discovering nucleic acid probes that have high affinity and high specificity for protein and cellular target s. Oligonucleotides discovered in these… More

Simple DNA/RNA Probes for Protein Targets

Award Year / Program / Phase:
2008 / SBIR / Phase I
Award Amount:
$194,084.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): We describe an integrated approach for rapid discovery of small, structurally defined nucleic acid probe sequences that bind with high affinity and selectivity to a target of interest. Such targets are proteins, bio- terror agents, pathogenic organisms and… More

Aptamer probes for Epigenetic Peptide Targets

Award Year / Program / Phase:
2010 / SBIR / Phase I
Award Amount:
$195,561.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): Epigenetic aberrations underlie the pathogenesis of a number of human diseases that lack clear genetic alterations. For example, mental health diseases such as bipolar disorder and schizophrenia are associated with epigenetic changes in the promoters of… More

Simple DNA/RNA Probes for Protein Targets

Award Year / Program / Phase:
2010 / SBIR / Phase II
Award Amount:
$1,587,554.00
Agency:
HHS
Principal Investigator:
Abstract:
DESCRIPTION (provided by applicant): We describe an integrated approach for High Throughput Screening of AptamersTM (HTSATM, patent pending) to discover small, structurally defined nucleic acid aptamer sequences that bind with high affinity and selectivity to a target of interest. Such targets are… More

Nanosensor Switches for Detection of Toxins, Pathogens, and Small Molecules

Award Year / Program / Phase:
2012 / STTR / Phase I
Award Amount:
$99,967.00
Agency / Branch:
DOD / USAF
Principal Investigator:
Mark McPike, CSO – (315) 299-7167
Research Institution:
Syracuse University
RI Contact:
Rebecca Bader
Abstract:
ABSTRACT: This phase I STTR project is a proof of concept study for developing near real-time, nanoparticle based sensors that detect the presence of specified toxins, pathogens, proteins, metabolites and small molecules. The specificity and sensitivity of this"nanosensor"is imparted by… More