USA flag logo/image

An Official Website of the United States Government

A METHOD FOR INCREASING THE HYBRIDIZATION EFFICIENCY OF DNA AND RNA PROBES

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
1632
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
1632
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Pacific Biotechnology Associat
8000 S.e. 35th Ave Portland, OR 97202
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1987
Title: A METHOD FOR INCREASING THE HYBRIDIZATION EFFICIENCY OF DNA AND RNA PROBES
Agency: NSF
Contract: N/A
Award Amount: $187,000.00
 

Abstract:

A METHOD FOR INCREASING THE SENSITIVITY OF NUCLEIC ACID HYBRIDIZATION REACTIONS INVOLVING NON-RADIOACTIVE DNA PROBES IS EXAMINED. PACIFIC BIOTECHNOLOGY RESEARCH ASSOCIATES HAS A PROPRIETARY METHOD WHICH INCREASES THE HYBRIDIZATION EFFICIENCY OF RADIOACTIVELY-LABELED GENETIC PROBES BY OVER 1000%. THIS METHOD WILL BE APPLIED TO COMMERCIALLY-AVAILABLE SYSTEMS WHICH PRODUCE NON-RADIOACTIVE DNA PROBES TO DETERMINE WHETHER THE SAME DEGREE OF AMPLIFICATION CAN BE OBTAINED IN A NON-RADIOISOTOPIC SYSTEM. SEVERAL MODIFICATIONS OF THE BASIC TECHNIQUE WILL BE TESTED IN ORDER TO DETERMINE THE OPTIMAL CONDITION FOR INCREASING THE SIGNAL OBTAINED WITH NON-RADIOACTIVE DNA PROBES.

Principal Investigator:

Karin D. Rodland Ph.d.
Vice President
0

Business Contact:

Karin d. rodland, ph.d.
VICE PRESIDENT
Small Business Information at Submission:

Pacific Biotechnology Associat
8000 S.e. 35th Ave Portland, OR 97202

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No