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THE OBJECTIVE OF THIS PROJECT IS TO SYNTHESIZE NEW GOSSYPOL DERIVATIVES FOR USE…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4846
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
4846
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Pacific Rim Bioscience
182 S Nardo Ave Solana Beach, CA 92075
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1986
Title: THE OBJECTIVE OF THIS PROJECT IS TO SYNTHESIZE NEW GOSSYPOL DERIVATIVES FOR USE AS MALE CONTRACEPTIVES.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE OBJECTIVE OF THIS PROJECT IS TO SYNTHESIZE NEW GOSSYPOL DERIVATIVES FOR USE AS MALE CONTRACEPTIVES. THE FACT THAT GOSSYPOL ITSELF IS ALREADY BEING USED AS A MALE CONTRA- CEPTIVE AGENT IN CHINA, AND THE NEED FOR AN INEXPENSIVE, REVERSIBLE, NONTOXIC MALE CONTRACEPTIVE IN DEVELOPING COUNTRIES INDICATES THAT NEW, MORE POTENT GOSSYPOL DERIVATIVES WILL BE COMMERCIALLY SUCCESSFUL. THE GOSSYPOL DERIVATIVES WILL BE TESTED FOR ABILITY TO INHIBIT ANDROGEN AND ESTROGEN BINDING TO PROTEINS, SPERM MOBILITY, AND SPERM METABOLISM. SUFFICIENT QUANTITIES OF THESE ANALOGUES FOR LATER IN VIVO STUDIES (PHASE II) WITH RATS AND HAMSTERS WILLPREPARED. LATER STUDIES (PHASE II) MAY ALSO INCLUDE TESTINGTHESE GOSSYPOL DERIVATIVES FOR ABILITY TO INHIBIT THE GROWTHOF TRYPANOSOMA CRUZI AND KILLING HERPES VIRUS.

Principal Investigator:

Michael e baker
PRINCIPAL INVESTIGATOR
6197557405

Business Contact:

Small Business Information at Submission:

Pacific Rim Bioscience Ent
182 South Nardo Ave Solana Beach, CA 92075

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No