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Three-Dimensional Matrices for Cellular and Multicellular Biointerfaces
- Small Business Information
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Woman-Owned: NoMinority-Owned: NoHUBZone-Owned: No
- Phase 1
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Fiscal Year: 1998Title: Three-Dimensional Matrices for Cellular and Multicellular BiointerfacesAgency / Branch: DOD / DARPAContract: N/AAward Amount: $98,981.00
Abstract:
Biological macromolecules are highly efficient at recognizing specific analytes or catalyzing reactions in aqueous biological media; however, their natural liquid environment limits military practicality. Any delineation from the preferred buffered aqueous environment results in partial or total loss of reactivity. It would be advantageous to immobilize biological macromolecules in alternative environments that stabilize them and preserve their reactivities. The proposed effort introduces a revolutionary matrix called aerogel to immobilize cells resulting in a biologically active solid matrix. Sof-gel chemistry will be utilized to immobilize the cells in the silica matrix. The silica matrix has an extremely large internal surface area, low density, high porosity, and adjustable pore size, which together render a highly efficient, lightweight matrix for cell immobilization. Also, the silica matrix provides a protective environment for cells, thus increasing shelf life and reactivity.Small Business Information at Submission:Principal Investigator:
Charles Daitch
8049233673Business Contact:
0PACIFIC-SIERRA RESEARCH CORP.
1400 Key Boulevard, Suite 700 Arlington, VA 22209EIN/Tax ID:DUNS: N/ANumber of Employees:Woman-Owned: NoMinority-Owned: NoHUBZone-Owned: No
Award Information
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Agency: Department of Defense |
Branch: Defense Advanced Research Projects Agency |
Award ID: 40425 |
Program Year/Program: 1998 / SBIR |
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Agency Tracking Number: 40425 |
Solicitation Year: N/A |
Solicitation Topic Code: N/A |
Solicitation Number: N/A |