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Company Information:

City: AIEA
State: HI
Zip+4: 96701
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,559,955.00 2
SBIR Phase II $2,695,398.00 1

Award List:

Inhibitors of Anthrax Lethal Factor Metalloproteinase

Award Year / Program / Phase: 2007 / SBIR / Phase II
Agency: HHS
Principal Investigator: Alan T. Johnson
Award Amount: $2,695,398.00
DESCRIPTION (provided by applicant): Anthrax Lethal Factor (LF) is a metalloproteinase introduced into the cells of mammalian hosts during infection by the bacterium Bacillus anthracis. LF disrupts intracellular signaling pathways mediated by the MAPKKs, r esulting in cell toxicity, sepsis,… More

Development of a Recombinant Subunit Ebola Vaccine

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Axel T. Lehrer
Award Amount: $959,998.00
DESCRIPTION (provided by applicant): Ebola and Marburg viruses, the only members of the family Filoviridae, cause hemorrhagic fevers which are lethal in up to 90% of human cases. No vaccine or antiviral therapy currently exists to prevent or treat Filoviru s infection. Due to their exceptional… More

Discovery of Broad Spectrum Dengue Virus Proteinase Inhibitors

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $599,957.00
DESCRIPTION (provided by applicant): Over half of the world population is at risk for infection by dengue virus, a mosquito borne member of the Flavivirus family that consists of four distinct serotypes. Approximately 50 to 100 million infections occur ann ually resulting in an estimated 500,000… More