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SBIR Phase I: Energy Efficient Manufacturing of Fluoroaromatics

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
88230
Program Year/Program:
2008 / SBIR
Agency Tracking Number:
0740056
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Pearlhill Technologies, LLC
616 S Adam Ln Idaho Falls, ID 83401-4629
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2008
Title: SBIR Phase I: Energy Efficient Manufacturing of Fluoroaromatics
Agency: NSF
Contract: 0740056
Award Amount: $100,000.00
 

Abstract:

The Small Business Innovation Research (SBIR) Phase I project proposes energy efficient microwave-process for the conversion of chloroaromatics to fluoroaromatics by halogen exchange. Currently, fluoroaromatics are produced by conventional heating of appropriate reagents; and potassium fluoride, the fluorinating agent, is poorly soluble in the reaction media. Unlike this process that involves rigorous drying, long reaction periods to obtain high yields while producing decomposition and side reactions, the alternative microwave process will use different fluorinating agents to produce similar yields in shorter reaction period, minimizes decomposition and side reactions, while significantly increasing the energy efficiency of the process. Fluoroaromatic constituents are active ingredients in many pharmaceutical and agrochemical formulations. These include PROZAC (cholesterol medication), PREVACID (ulcer and acid reflux treatment), FLONASE (anti-asthma agent), FLUXETINE (an antidepressant agent), FLUVOXAMINE (an antidepressant), EFFAVIRENZ (antiretroviral therapy for HIV), and MEFLOQUINE (anti-malarial). Others include NORFLURAZON FLURIDONE (herbicides), FLURPRIMIDOL (plant regulator), FLUOTRIMAZOLE and FLUTRIAFOL (fungicides). Over the next decade, some 33 percent of pharmaceuticals drugs, and 9 percent of agrochemicals would be fluorinated, worth over $15 billion in sales. The current manufacturing technology, by conventional heating, consumes several trillion BTU/year. This work will produce technologies that will conserve several billion BTU/year in future manufacturing of fluoroaromatics.

Principal Investigator:

Bamidele A. Omotowa
PhD
2085232266
bomotowa@yahoo.com

Business Contact:

Bamidele A. Omotowa
PhD
2085232266
bomotowa@yahoo.com
Small Business Information at Submission:

Pearlhill Technologies, LLC
616 S Adam Ln Idaho Falls, ID 83401

EIN/Tax ID: 711032501
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No