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SIMPLE DIAGNOSTIC SYSTEM FOR MYOCARDIAL INFARCTION

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
13960
Program Year/Program:
1990 / SBIR
Agency Tracking Number:
13960
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Pegasus Technologies Inc
5970 Heisley Road Mentor, OH 44060
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Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1990
Title: SIMPLE DIAGNOSTIC SYSTEM FOR MYOCARDIAL INFARCTION
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

OVER 1.5 MILLION PEOPLE HAVE HEART ATTACKS IN THE UNITED STATES EVERY YEAR AND OVER HALF A MILLION DIE AS A RESULT. RAPID AND ACCURATE DIAGNOSIS AFTER THE ONSET OF SYMPTOMS IS IMPORTANT NOT ONLY TO INSTITUTE PROPER THERAPY BUT ALSO TO RULE OUT MYOCARDIAL INFARCTION (MI). BECAUSE ELECTROCARDIOGRAMS CAN BE MISLEADING, A NUMBER OF LABORATORYENZYME TESTS HAVE BEEN USED TO DIAGNOSE MI, BUT THESE PROCEDURES ARE OFTEN NOT AVAILABLE AT ALL HOURS. RECENT LITERATURE SUPPORTS THE RATIO OF SERUM LACTATE DEHYDROGENASE ISOENZYME-1 (LD-1) TO TOTAL LD AS THE BEST LABORATORY TEST FOR MI. PRESENT METHODS FOR DETERMINATION OF LD-1 ARE TEDIOUS, TIME CONSUMING, COSTLY, AND DIFFICULT TO AUTOMATE. AUTOMATION IS THE BEST APPROACH TO ACCURATE AND RAPID LABORATORY ANALYSES. THE PROPOSED SYSTEM IS A SIMPLE AUTOMATED ANALYZER THAT RAPIDLY PERFORMS BOTH LD-1 AND TOTAL LD DETERMINATIONS WITH A SINGLE, STABLE REAGENT SYSTEM. THE FEASIBILITY OF THE REAGENT DESIGN HAS BEEN DEMONSTRATED. THE GOALS OF THE PHASE I PROJECT ARE TO COMPLETE THE REAGENT DEVELOPMENT AND BUILD A BREADBOARD INSTRUMENT. THE INSTRUMENT WILL BE EASY FOR BOTH THE MAIN LABORATORY AND THE CORONARY CARE UNIT STAFF TO USE, AND IT WILL BE AVAILABLE FOR STAT SAMPLES AT ANY TIME.

Principal Investigator:

Arthur L Babson
2018792129

Business Contact:

Small Business Information at Submission:

Pegasus Technologies Inc
Po Box 15 Chester, NJ 07930

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No