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Company Information:

Company Name: Pharmos Corporation
City: Alachua
State: FL
Zip+4: 32615
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: (904) 462-1210

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $545,331.00 10
SBIR Phase II $1,696,783.00 4

Award List:

CHELATING AGENTS

Award Year / Program / Phase: 1986 / SBIR / Phase I
Agency: DOE
Principal Investigator: Dr. efraim shek , PRINCIPAL INVESTIGATOR
Award Amount: $50,000.00
Abstract:
Most chelating agents that are effective in decorportation radionuclides from patients exposed to them are not effective when administered orally. dtpa is an example of achelating agent which has to be given i.v. on a daily basis to remove effectively plutonium from the skeleton and other soft… More

ORAL DELIVERY OF A SUSTAINED ESTRADIOL DELIVERY SYSTEM

Award Year / Program / Phase: 1987 / SBIR / Phase I
Agency: HHS
Principal Investigator: Kerry S Estes Phd
Award Amount: $50,000.00

IMPROVED DELIVERY OF ANTIVIRALS FOR CNS INFECTIONS

Award Year / Program / Phase: 1988 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00
Abstract:
Human cytomegalovirus (hcmv) is a common and not usually serious infective agent. however, in the case of acquired immunodeficiency syndrome (aids) and other immuno-suppressedstates, hcmv is inordinately virulent and is even a major cause of death. recently, treatment of hcmv infections in… More

ORAL DELIVERY OF A SUSTAINED ESTRADIOL DELIVERY SYSTEM

Award Year / Program / Phase: 1988 / SBIR / Phase II
Agency: HHS
Principal Investigator: Kerry S Estes Phd
Award Amount: $462,000.00
Abstract:
Studies are proposed to evaluate the feasibility of oral 17beta-estradiol (e2) administration using a novel redox system. this chemical delivery system (cds) is based on an interconversion of a lipophilic dihydropyridine to a hydrophilic pyridinium salt, analogous to the nadh nad+ coenzyme system.… More

PRODUCTION SYNTHESIS OF INSULIN-LIKE GROWTH FACTOR II SYNTHESIS OF IMPROVED DELIVERY FORMS OF ANTIVIRAL AGENTS

Award Year / Program / Phase: 1988 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00
Abstract:
New methods are needed which will allow for the routine production by solid phase synthesis of peptides of 60 to 70 amino acids in length on the 50 to 100 gram scale. currently, peptides can be made either by solid phase synthesis techniques on small scale (up to 5 gm) or by genetic engineering:… More

CROSS-AXIS COIL PLANET CENTRIFUGE CHROMATOGRAPH DESIGN AND SYNTHESIS OF BRAIN-SPECIFIC ANTIHERPETIC AGENTS

Award Year / Program / Phase: 1988 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00

CROSS-AXIS COIL PLANET CENTRIFUGE CHROMATOGRAPH DESIGN AND SYNTHESIS OF BRAIN-SPECIFIC ANTIHERPETIC AGENTS

Award Year / Program / Phase: 1989 / SBIR / Phase II
Agency: HHS
Principal Investigator:
Award Amount: $416,005.00
Abstract:
A new countercurrent chromatography instrument, the cross-axis flow-through coil planet centrifuge is proposed for the preparative chromatography of peptides. this is an apparatus that separates substances according to their partitioning in a liquid-liquid equilibration system withoutthe use of a… More

IMPROVED THERAPY FOR CNS TOXOPLASMOSIS

Award Year / Program / Phase: 1989 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00
Abstract:
Cerebral toxoplasmosis is the most common opportunistic disease affecting the brain of patients with acquired immunedeficiency syndrome (aids). sulfonamide treatment is initially effective in treating the infection, but the regimen often causes side effects that limit therapy, subsequently provoking… More

IMPROVED THERAPY FOR DEPRESSION

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: HHS
Principal Investigator: Emil Pop
Award Amount: $50,000.00
Abstract:
Depression is a heterogenous disease, covering a range of severity, qualities, and causes that affects an important portion of population. none of the available treatment modalities of depression, including electroconvulsive therapy and pharmacotherapy mainly by tricyclics and monoamine oxidase… More

DEVELOPMENT OF A NONSURFACTANT FORMULATION FOR INDUCING AGENTS

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: HHS
Principal Investigator: Wesley R Anderson
Award Amount: $45,390.00

PARENTERAL FORMULATION FOR CARBAMAZEPINE

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Kerry Estes
Award Amount: $49,941.00

DEVELOPMENT OF A NONSURFACTANT FORMULATION FOR INDUCING AGENTS

Award Year / Program / Phase: 1992 / SBIR / Phase II
Agency: HHS
Principal Investigator: Wesley R Anderson
Award Amount: $318,778.00
Abstract:
Adverse reactions have been reported to occur after administration of compounds solubilized in aqueous vehicles. these side effects may be reduced or eliminated by combining the primary inducing agent, alfaxalone, with cyclodextrins, which have been shown to improve solubility and efficacy of other… More

PARENTERAL FORMULATION FOR CARBAMAZEPINE

Award Year / Program / Phase: 1992 / SBIR / Phase II
Agency: HHS
Principal Investigator: Kerry Estes
Award Amount: $500,000.00
Abstract:
The favorable efficacy, toxicity and adverse side-effect profiles of carbamazepine (cbz) contribute to its widespreadand increasing use to control seizures in the epiletptic patients. however, in cases when oral drug treatment is notfeasible, no parenteral formulation is available for cbz. currently… More

PRODRUGS AND AQUEOUS FORMULATIONS OF DEXANABINOL

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Pop, emil
Award Amount: $100,000.00