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DEVELOPMENT OF A NONSURFACTANT FORMULATION FOR INDUCING AGENTS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
13899
Program Year/Program:
1992 / SBIR
Agency Tracking Number:
13899
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Pharmos Corporation
2 INNOVATION DR Alachua, FL 32615
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1992
Title: DEVELOPMENT OF A NONSURFACTANT FORMULATION FOR INDUCING AGENTS
Agency: HHS
Contract: N/A
Award Amount: $318,778.00
 

Abstract:

ADVERSE REACTIONS HAVE BEEN REPORTED TO OCCUR AFTER ADMINISTRATION OF COMPOUNDS SOLUBILIZED IN AQUEOUS VEHICLES. THESE SIDE EFFECTS MAY BE REDUCED OR ELIMINATED BY COMBINING THE PRIMARY INDUCING AGENT, ALFAXALONE, WITH CYCLODEXTRINS, WHICH HAVE BEEN SHOWN TO IMPROVE SOLUBILITY AND EFFICACY OF OTHER STEROIDS. PRELIMINARY STUDIES IN A RAT MODEL SHOW PROMISE FOR THIS COMBINATION. SUCCESSFUL DEVELOPMENT OF THIS TECHNIQUE WILL PROVIDE A SAFE ALTERNATIVE FOR A NONSURFACTANT FORMULATION FOR THE INDUCINGAGENT, REDUCING TOXIC SIDE EFFECTS AND ALLOWING SAFE AND RELIABLE ANESTHESIA.

Principal Investigator:

Wesley R Anderson
9044621210

Business Contact:

Small Business Information at Submission:

Pharmatec Inc.
Po Box 730 Alachua, FL 32615

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No