This study is for the synthesis of high performance ultrafine si(3)n(4) ceramic material (1 micron or less sperical particles) by reacting nitrogen gas with a beam of molten silicon micro-droplets. this single-step process is expected to provide reaction bonded material with excellent oxidation and… More

This proposal is for the development of an innovative liquidchromatography-mass specrometry (lc/ms) interface. the approach involves using crossed-beam technology together with sputtering secondary molecular ions from liquid droplet surfaces. phase i will test the validity of this approach.

The long-term objective of this research is to develop instrumentation for the mass analysis of proteins and other biological macromolecules in the range of 10,000 to 100,000 amu. the specific aim of phase i is to demonstrate the feasibility of producing protein molecular ions generated byion… More

The long-term objectives of this project are twofold: to provide a clear understanding of the physical mechanisms governing the increases in detection sensitivity demonstrated to date by the proposed methodology and to construct prototype hardware from which commercial high-massdetection… More

The long-term objectives of this project are threefold: to provide improved commercial instrumentation for particle-induced desorption of large, fragile molecules, to increase overall secondary ion yield efficiencies of low mass ions as well and to add additional insight for improving existing… More

This project is to develop a new technology to obtain sequence information on proteinsseparated by 2D-gel electrophoresis. This instrument will be capable of sequencing multiple samplessimultaneously, with greater sensitivity than that obtained with current technology. These features willgreatly… More

Maxios Laser Corporation proposes to investigate in Phase 1 a laser diode pumped Er:YAG/ sapphire waveguide laser at 2.94 um as representative of a family of new laser systems which show potential to build more compact laser systems at high beam quality. We plan to design and start to build in Phase… More