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STUDY OF EXERCISE PERFORMANCE USING 31P NMR AND AN ISOKINETIC ERGOMETER

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4995
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
4995
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Phospho-energetics Inc.
3401 Market Street Suite 320 Philadelphia, PA 19104
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1987
Title: STUDY OF EXERCISE PERFORMANCE USING 31P NMR AND AN ISOKINETIC ERGOMETER
Agency: HHS
Contract: N/A
Award Amount: $118,000.00
 

Abstract:

PHOSPHO-ENERGETICS, INC. (P-E) HAS DEVELOPED AN NMR SPECTRO-METER FOR THE VALIDATION OF 31P IN DISEASED AND NORMAL HUMANTISSUES; BASED UPON THAT PROCESS, P-E HAS NOW DEVELOPED A COMBINATION NMR/WORK OUTPUT MEASURING INSTRUMENT. STUDIES HAVE BEEN PERFORMED WITH SUBJECTS SUFFERING FROM PERIPHERAL VASCULAR DISEASE, GENETIC DEFECTS, AND CARDIOMYOPATHY, AS WELL AS NORMAL VOLUNTEERS AND ATHLETES LEADING TO A DATABASEFROM WHICH THE RATIOS OF VARIOUS PHOSPHATES, E.G., PHOSPHO- CREATINE/INORGANIC PHOSPHATE (PCR/PI), PHOSPHO DIESTERS/PI, AND SUGAR PHOSPHATES/PI, MAY BE USED TO DETERMINE THE STATE OF THE TISSUE. IT IS PROPOSED TO EXTEND THIS WORK INTO A STUDY OF "APPARENT" NORMAL VOLUNTEERS BETWEEN THE AGES OF 65AND 75 TO TRY AND CORRELATE THE EXISTING DATA WITH ONGOING MEASUREMENTS RELATIVE TO AN EXERCISE PROTOCOL AND NUTRITION-AL PROTOCOL. TO DO THIS, P-E MUST DEVELOP A NEW, NONMAGNET-IC LINKAGE SUITABLE FOR IN-MAGNET LEG EXERCISE. IT IS EXPECTED THAT THE COMBINED 31P NMR, NON-MAGNETIC LINKAGE ANDERGOMETER COULD BECOME COMMERCIALLY IMPORTANT AS A SCREENINGTEST (1) TO IDENTIFY INCIPIENT PVD OR DIABETES AND (2) TO EVALUATE THE EFFECT OF EXERCISE AND THE RELATIONSHIP BETWEENEXERCISE AND NUTRITION IN THE AGING POPULATION.

Principal Investigator:

Roger Wheatley
Principal Investigator
2153874429

Business Contact:

Small Business Information at Submission:

Phospho-energetics Inc.
3401 Market Street Suite 320 Philadelphia, PA 19104

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No