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TEA-CO2 DEBRIDEMENT OF BURN ESCHAR (7130-260)

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
16615
Program Year/Program:
1991 / SBIR
Agency Tracking Number:
16615
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Physical Sciences Inc.
20 New England Business Center Andover, MA 01810-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1991
Title: TEA-CO2 DEBRIDEMENT OF BURN ESCHAR (7130-260)
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE OBJECTIVE OF THIS PROJECT IS TO INVESTIGATE THE FEASIBILITY OF UTILIZING COMMERCIALLY AVAILABLE REPETITIVELY-PULSED CO2 TEA LASER TECHNOLOGY FOR THE PRECISE, CONTROLLED DEBRIDEMENT OF BURN ESCHAR IN THE TREATMENT OF FULL THICKNESS DERMAL BURNS. PRELIMINARY INVESTIGATIONS SUGGEST THAT THE NARROW ZONE OF THERMALLY-COAGULATED TISSUE LEFT BY THE CO2 TEA LASER COULD PROVIDE NEARLY OPTIMUM CONDITIONS FOR SKIN GRAFTING. PHASE I STUDIES WILL INVOLVE ANIMAL EXPERIMENTS TO ASSESS THE EFFECTIVENESS OF THE TEA LASER FOR DEBRIDING ESCHAR FROM CONTROLLED FULL THICKNESS DERMAL BURNS. QUANTITATIVE MEASUREMENTS WILL BE MADE OF THE ABLATION RATE AS WELL AS THE EXTENT OF RESIDUAL THERMAL DAMAGE FOUND IN THE UNDERLYING TISSUE. ALSO INVESTIGATED WILL BE THE UTILITY OF USING FAST, REAL-TIME PHOTOTHERMAL RADIOMETRY AS FEEDBACK GUIDANCE FOR DETERMINING WHEN THE NECROTIC/VIABLE TISSUE INTERFACE HAS BEEN REACHED. IF SUCCESSFUL, THIS RESEARCH WOULD LEAD TO THE DEVELOPMENT OF A SIGNIFICANTLY IMPROVED TECHNIQUE FOR THE RAPID, PRECISE, AND CONTROLLED DEBRIDEMENT OF BURN ESCHAR WITH MINIMAL BLOOD LOSS AND DAMAGE TO UNDERLYING VIABLE TISSUE. THE OBJECTIVE IS TO INCREASE THE SUCCESS WITH WHICH DERMAL AND EPIDERMAL TISSUE CAN BE GRAFTED THEREBY LOWERING MORBIDITY AND MORTALITY AND IMPROVING COSMETIC APPEARANCE.

Principal Investigator:

Rosen, David I
Principal Investigator
5086890003

Business Contact:

1 r43 gm43676-01a1
Small Business Information at Submission:

Physical Sciences, Inc
20 New England Business Center Andover, MA 01810

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No