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Field-Deployable Imaging System to Assess Potential Retinal Injuries

Award Information

Department of Defense
Air Force
Award ID:
Program Year/Program:
2005 / STTR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Physical Sciences Inc.
20 New England Business Center Andover, MA 01810-1077
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2005
Title: Field-Deployable Imaging System to Assess Potential Retinal Injuries
Agency / Branch: DOD / USAF
Contract: FA9550-04-C-0136
Award Amount: $99,996.00


Advanced imaging technologies now exist to detect the tissue changes that occur due to retinal laser injuries that may not be visible with fundus photography. Very recent developments at Physical Sciences Inc. (PSI) and the Wellman Center for Photomedicine have made it possible to combine these technologies into a single, affordable field-deployable device. The Line-Scanning Laser Ophthalmoscope (LSLO) is a compact, low-cost, quasi-confocal SLO imaging system. High quality, high resolution and high contrast wide-field en face retinal SLO images are obtained non-mydriatically with <600¿YW of NIR source power at up to 30 frames/sec. Images are captured, processed and displayed with integrated FPGA and LCD technology. Simultaneously, revolutionary advances have been made in the field of optical coherence tomography (OCT), pioneered by researchers at the Wellman Center for Photomedicine. New implementations of spectral domain OCT (SD-OCT) have produced more efficient and compact OCT designs with few moving parts and a thousand-fold multiplex advantage over conventional OCT. Full SD-OCT images are obtained non-mydriatically, with <600¿YW of broadband illumination at up to 30 frames/sec. The architecture that PSI has already developed for hand-held LSLO applications, is ideally suited to the incorporation of SD-OCT. In Phase I, a hybrid LSLO/SD-OCT system will be demonstrated, that offers superior retinal imaging in a compact, portable package.

Principal Investigator:

R. D. Ferguson
Principal Research Scientist

Business Contact:

B. D. Green
Executive VP/R&D Operations
Small Business Information at Submission:

Physical Sciences, Inc.
20 New England Business Center Andover, MA 01810

EIN/Tax ID: 042517090
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
Wellman Center for Photomedici, 50 Blossom Street
Boston, MA 02114
Contact: Johannes F. de Boer
Contact Phone: (617) 724-2202
RI Type: Domestic nonprofit research organization