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Fine Chemicals from Agricultural Residues

Award Information

Department of Agriculture
Award ID:
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Plant Polyphenols, LLC
P. O. Box 12522 Alexandria, LA 71315
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Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2002
Title: Fine Chemicals from Agricultural Residues
Agency: USDA
Contract: 2002-33610-11801
Award Amount: $58,554.00


Flavonoids and proanthocyanidins are potent anti-oxidants and have recently found considerable interest in their potential for reducing risks or treatments of heart disease, cancer, and microbial infections. To make further progress in understanding the biological significance of these compounds, it is necessary to provide biologists with gram to kilogram amounts of pure compounds at a reasonable price. It is also necessary to be able to assure the potential to produce tonnage quantities should drug discovery and development be successful. Because oligomeric proanthocyanidins are usually found in only low concentrations even in plant tissues containing high concentrations of tannins, production of these compounds in gram quantities by direct extraction is usually not feasible. Therefore, this research is directed to optimizing ways to use abundant agricultural waste products as a source of flavan-3-ol derivatives that can be used as intermediates in the "semi-syntheses" of a wide variety of plant proanthocyanidin derivatives. Successful development of processes to produce these flavan-3-ol derivatives will open the door to production of a wide variety of proanthocyanidin derivatives and allow us to optimize the biological properties of these compounds.

Principal Investigator:

Richard W. Hemingway

Business Contact:

Richard W. Hemingway
Small Business Information at Submission:

Plant Polyphenols, LLC
P. O. Box 12522 Alexandria, LA 71315

EIN/Tax ID: 721511045
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No