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Biophotonic Detection of WNV Antibodies

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
54236
Program Year/Program:
2001 / SBIR
Agency Tracking Number:
1R43AI049687-01
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
PLATYPUS TECHNOLOGIES, LLC
5520 Nobel Drive Suite 100 Madison, WI 53711-4910
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2001
Title: Biophotonic Detection of WNV Antibodies
Agency: HHS
Contract: N/A
Award Amount: $297,999.00
 

Abstract:

DESCRIPTION (provided by applicant):The investigation of an epizootic presents the challenge of detecting antibodies in multiple species. ELISA, the method commonly used for screening large numbers of samples for antibodies, requires species-specific secondary antibodies. In the recent outbreak of West Nile virus in New York City, at least 18 species of birds, as well as horses and humans have been infected with the virus. Platypus technology is based on the exquisite sensitivity of liquid crystals to nanometer scale changes in surface topography of thin films of gold. The binding of antibodies from any species to specific receptors displayed on the surface is reported within seconds by the transduction of visible light through a liquid crystal cell. This platform technology is rapid, sensitive (1000 molecules can be detected), suitable for low technology environments and is adaptable to automation. It will find numerous applications in research, clinical diagnostics, epidemiology, drug discovery and many other areas. We will develop an assay to detect West Nile virus antibodies from any species based on this technology. PROPOSED COMMERCIAL APPLICATION: Platypus technology is a broad-based platform technology that will have application in all fields where the detection of molecular interactions is critical. There is a growing market for rapid viral diagnostics. Our technology can bring diagnosis closer to the point of care. The ability to detect antibodies from multiple species will be of great value to epidemiologic studies.

Principal Investigator:

Barbara A. Israel

Business Contact:


6082652454
MURPHYC@SVM.VETMED.WISC.EDU
Small Business Information at Submission:

PLATYPUS TECHNOLOGIES, LLC
505 S ROSA RD MADISON, WI 53719

EIN/Tax ID: 391992935
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No