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In-vivo Confocal Spectropolarimetric Imaging

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
85399
Program Year/Program:
2007 / SBIR
Agency Tracking Number:
CA124035
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Polaris Sensor Technologies
200 Westside Square Suite 320 Huntsville, AL 35801-4875
View profile »
Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2007
Title: In-vivo Confocal Spectropolarimetric Imaging
Agency: HHS
Contract: 1R43CA124035-01A2
Award Amount: $168,778.00
 

Abstract:

DESCRIPTION (provided by applicant): The objective of the research proposed here is to develop and apply an in-vivo spectral optical imaging technique called confocal polarimetric imaging for the diagnosis of human skin lesions. The broader objectives inc lude correlating the pathology of skin lesions to the acquired imagery and ultimately improving clinicians' diagnostic capabilities for skin lesions and their margins. The research is aimed at improving the diagnosis specificity of benign versus. (pre)mali gnant lesions and improving classification capabilities to preclude unwarranted invasive procedures such as biopsy and excision. Specific aims of the research include the design, construction, calibration, testing, and validation of a multimodality imager, coupled with a limited preliminary clinical trial to assess the technique's merit. It is expected that the high contrast imaging capabilities of confocal microscopy coupled with the morphologically sensitive technique of spectropolarimetric imaging will y ield a more informative data cube that may be exploited for lesion discrimination purposes. In conjunction with a dermatologist and dermatopathologist, the device will be used to image skin lesions and the results correlated to clinical diagnoses and derma topathology findings to assess its usefulness. The approach is expected to concurrently exploit the known advantages of the component imaging techniques to yield more informative architectural information about skin lesions, permitting improved in-vivo dia gnostic capabilities vis- -vis traditional imaging approaches.

Principal Investigator:

Arthur Lompado
2565620087
ART@POLARISSENSOR.COM

Business Contact:

Chenault
david@polarissensor.com
Small Business Information at Submission:

POLARIS SENSOR TECHNOLOGIES, INC.
POLARIS SENSOR TECHNOLOGIES, INC. 200 WESTSIDE SQ, STE 320 HUNTSVILLE, AL 35801

EIN/Tax ID: 431998920
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No