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Novel Antibacterial Agents

Award Information

Department of Defense
Award ID:
Program Year/Program:
2009 / STTR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
PolyMedix, Inc.
170 N. Radnor-Chester Road RADNOR, PA -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2009
Title: Novel Antibacterial Agents
Agency / Branch: DOD / NAVY
Contract: N00014-09-M-0357
Award Amount: $69,891.00


The need for novel antibiotics is well understood by anyone familiar to the field. We have discovered a novel class of antibiotics that are structurally unique from all previously known antibiotics and appear to operate via a distinctive mode of action. As a result, these new agents appear to represent significant promise as new treatments for the emerging problem of MDR infections. In less than 5 years, PolyMedix has translated one of these novel molecules from discovery to Phase 1a human clinical trials with a planned indication to broadly treat Staphylococcal infections including methicillin-resistant S. aureus. This proposal describes our efforts to develop lead compounds against those pathogens most relevant to military personnel with a specific focus on Acinetobacter and P. aeruginosa.

Principal Investigator:

Richard W. Scott
VP Research, PolyMedix

Business Contact:

Dawn Eringis
Director Scientific Affairs, PolyMe
Small Business Information at Submission:

PolyMedix, Inc.
170 N. Radnor-Chester Road Suite 300 Radnor, PA 19087

EIN/Tax ID: 270125925
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
University of Massachusetts, Amhers
Research Administration Bldg
70 Butterfield Terrace
Amherst, MA 1003
Contact: Carol P. Sprague
Contact Phone: (413) 545-0698
RI Type: Nonprofit college or university