Simultaneous Near-Field and Confocal Imaging

DESCRIPTION (provided by applicant): Recent developments in near-field
instrumentation have provided PRAIRIE TECHNOLOGIES with the necessary
understanding to develop a multi-mode confocal microscope that will integrate
confocal microscopy with simultaneous high-speed fluorescence measurements as
well as sub-diffraction resolution imaging. This powerful new tool will
revolutionize scientists' ability to study neuronal function and dysfunction in
living systems. In phase I we will build and test an alpha prototype by
integrating a high-speed fluorescence detection path into our existing confocal
microscope. In phase II, we will use the knowledge gained in this phase I
feasibility to design and build a commercial simultaneous near-field and
confocal imaging system.

The resultant product will permit the scientist to address significant
questions concerning ion fluxes, synaptic transmission and the molecular nature
of learning and memory.

PROPOSED COMMERCIAL APPLICATION:
Not Available