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Company Information:

Company Name: PRIMORIGEN BIOSCIENCES, INC.
City: MADISON
State: WI
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $2,214,467.00 7
SBIR Phase II $4,201,929.00 3

Award List:

Novel Assay for Rapid Antibody Screening

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $362,714.00
Abstract:
DESCRIPTION (provided by applicant): Primorigen Biosciences will use Phase I SBIR funds to develop a frameless, multiplexed, microarray screening system for rapid identification and characterization of antibody matched pairs with appropriate affinity and specificity for target proteins. This… More

A Novel Multiplexed Assay for Rapid Antibody Screening

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency: HHS
Principal Investigator: Scott A. Monsma
Award Amount: $1,569,693.00
Abstract:
DESCRIPTION (provided by applicant): Primorigen Biosciences will use Phase II SBIR funds to accelerate and expand the development of new regenerative medicine cell therapies by developing a novel high throughput, low cost protein quantification system for characterizing pancreatic 2 cell and islet… More

New Multiplexed Quantitative Detection of Pluripotency and Germ Layer Proteins

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency: HHS
Principal Investigator: Scott A. Monsma
Award Amount: $1,395,253.00
Abstract:
DESCRIPTION (provided by applicant): Primorigen Biosciences will use Phase II SBIR funds to accelerate and expand the development of new regenerative medicine cell therapies by developing a novel high throughput, low cost protein quantification system for characterizing pluripotent cell lines and… More

A Novel System for Mass Production of iPS Cells

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Scott A. Monsma – 608-441-8331
Award Amount: $343,865.00
Abstract:
DESCRIPTION (provided by applicant): Primorigen Biosciences LLC SBIR Project Abstract Primorigen will use SBIR funds to develop and validate a microcarrier-based cell culture system for selection, scale-up and feeder-free mass production of iPS cells, based on Primorigen's proprietary… More

A Novel Method to Improve Function of SC-Derived Hepatocytes

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Scott A. Monsma – 608-441-8332
Award Amount: $328,224.00
Abstract:
DESCRIPTION (provided by applicant): Primorigen Biosciences SBIR Proposal Abstract Primorigen Biosciences will use SBIR funds to develop an advanced cell culturing methodology to increase the efficiency of directed differentiation and to boost functional maturity of induced pluripotent stem… More

A Novel Method to Improve Proliferation and Neural Induction of Human MSCs

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Bradley H. Garcia – 608-441-8332
Award Amount: $344,715.00
Abstract:
DESCRIPTION (provided by applicant): Primorigen Biosciences will develop an enhanced cell culturing technology that dramatically increases proliferative and differentiation capabilities of human bone-marrow derived mesenchymal stem cells (hMSC's) for neural induction, and ultimately for… More

hiPS Derived Assay for Screening Hematopoietic Differentiation Toxicant Effects

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: HHS
Principal Investigator: Bradley H. Garcia – 608-628-5189
Award Amount: $210,823.00
Abstract:
Primorigen Biosciences (R) Abstract Primorigen Biosciences will use SBIR funds to develop a high-throughput toxicology assay system utilizing human ventricular cardiomyocytes (vCMs) differentiated from human induced pluripotent stem cells (hiPSCs). Phase Istudies will convert the small-molecule… More

Polynitroxylated Pegylated Hemoglobin for Traumatic Brian Injury Resuscitation

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: HHS
Principal Investigator: Bradley H. Garcia – 608-628-5189
Award Amount: $224,479.00
Abstract:
Primorigen Biosciences (R) Abstract Primorigen Biosciences will use SBIR funds to develop a novel commercial assay that measures the toxicity of compounds on human induced pluripotent stem cells (hiPSCs) differentiating into hematopoietic progenitor cells(HPCs) and on HPCs differentiated from… More

Ellipsoid Particles for High Performance LC Separations

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: HHS
Principal Investigator: Scott A. Monsma – 608-441-8332
Award Amount: $399,647.00
Abstract:
DESCRIPTION (provided by applicant): Primorigen will use SBIR SHIFT funds to develop an array system that can identify chemically-defined surfaces to optimize induced pluripotent stem cell (hiPSC) differentiation and maturation. The platform initially willbe validated for its capacty to help… More

A Novel 3-D System for Cost-Effective Industrial Production of Pluripotent Cells

Award Year / Program / Phase: 2013 / SBIR / Phase II
Agency: HHS
Principal Investigator: Bradley H. Garcia – 608-628-5189
Award Amount: $1,236,983.00
Abstract:
DESCRIPTION (provided by applicant): Primorigen Biosciences (R) Abstract Primorigen Biosciences will use Phase II SBIR funds to advance its novel, 3-dimensional system for robust expansion of induced pluripotent stem cells (iPSCs) by a) scaling up iPSC production in 3L bioreactors, b) validating the… More