CCD CAMERA SYSTEM FOR X-RAY DIFRACTION IMAGING

Award Information

Agency: Department of Health and Human Services	Branch: N/A	Award ID: 11383	Program Year/Program: 1991 / SBIR
Agency Tracking Number: 11383	Solicitation Year: N/A	Solicitation Topic Code: N/A	Solicitation Number: N/A

Small Business Information: PRINCETON SCIENTIFIC INSTRUMENTS, INC.
7 Deer Park Drive Suite C Monmouth Junction, NJ -
View profile »

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No

Phase 2: Fiscal Year: 1991

Title: CCD CAMERA SYSTEM FOR X-RAY DIFRACTION IMAGING

Agency: HHS

Contract: N/A

Award Amount: $500,000.00

Abstract:
THIS PROJECT WILL INVESTIGATE THE ADVANTAGES OF A NEW 2,048 X 2,048-PIXEL CCD-TYPE SOLID-STATE IMAGE SENSOR FOR X-RAY DIFFRACTION APPLICATIONS ON BIOLOGICAL MACROMOLECULES. THE CCD WILL BE FIBEROPTICALLY COUPLED DIRECTLY TO AN X-RAY-SENSITIVE PHOSPHOR SCREEN, ELIMINATING THE IMAGE INTENSIFIER NORMALLY EMPLOYED IN SUCH X-RAY DIFFRACTION IMAGING EQUIPMENT. THIS RESULTS IN A SUBSTANTIAL IMPROVEMENT IN SPATIAL RESOLUTION AND DYNAMIC RANGE. THE PROJECT INCLUDES DESIGNING AND BUILDING THE FIXTURE FOR MOUNTING THE CCD AND FIBEROPTICS PHOSPHOR SCREEN TOGETHER, CONDUCTING THE EXPERIMENTS, AND ANALYZING THE DATA. THE PHASE I PROGRAM WILL INVESTIGATE THE ADVANTAGES OF THESE NEW IMAGE SENSORS TO X-RAY-DIFFRACTION-RELATED RESEARCH. THE HIGH RESOLUTION AND WIDE DYNAMIC RANGE OF THIS CCD IMAGING SYSTEM IS PARTICULARLY WELL MATCHED TO THE PROBLEM OF X-RAY LAUE DIFFRACTION FROM PROTEIN CRYSTALS USING SYNCHROTRON-GENERATED POLYCHROMATIC X-RAYS AND PROTEINDIFFRACTION FROM LARGE UNIT CELLS, A PHASE II EFFORT.

Principal Investigator:

0

Business Contact:

Small Business Information at Submission:

Princeton Scientific Instrumnt
306 Alexander St Princeton, NJ 08540

EIN/Tax ID: 222287510

DUNS: N/A

Number of Employees: N/A

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No