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THE PURPOSE OF THIS RESEARCH IS TO DEVELOP A RAPID, SIMPLE, INEXPENSIVE, AND…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4677
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
4677
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Princeton Separations Inc
37 Nottingham Road Englishtown, NJ 07726
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1986
Title: THE PURPOSE OF THIS RESEARCH IS TO DEVELOP A RAPID, SIMPLE, INEXPENSIVE, AND SENSITIVE FLUORESCENCE POLARIZATION IMMUNOASSAY SYSTEM THAT CAN BE USED IN THE DOCTOR'S OFFICE TO MONITOR DRUGS AND HORMONES IN THE SERA OF A PATIENT DURING HIS VISIT.
Agency: HHS
Contract: N/A
Award Amount: $43,000.00
 

Abstract:

THE PURPOSE OF THIS RESEARCH IS TO DEVELOP A RAPID, SIMPLE, INEXPENSIVE, AND SENSITIVE FLUORESCENCE POLARIZATION IMMUNOASSAY SYSTEM THAT CAN BE USED IN THE DOCTOR'S OFFICE TO MONITOR DRUGS AND HORMONES IN THE SERA OF A PATIENT DURING HIS VISIT. THE FLUORESCENCE POLARIZATION IMMUNOASSAYSYSTEM CAN DETECT ANALYTES IN SERA IN THE MICROGRAM PER MILLILITER TO SUBNANOGRAM PER MILLILITER RANGE WITH A PROCEDURE REQUIRING LESS THAN FIVE MINUTES. IT IS A HOMOGENEOUS ASSAY THAT OVERCOMES THE LIMITATIONS OF FLUORESCENCE IMMUNOASSAY MEASUREMENTS BY USING SPECIAL PROBES AND ELIMINATING NON-SPECIFIC BINDING OF PROBES AND ANALYTES. PRINCETON SEPARATIONS, INC. HAS AIMED TO SHOW THAT THREE ANALYTES (DIPHENYLHYDANTOIN, THYROXINE, AND DIGOXIN) CAN BE DETECTED IN SERA WITH COEFFICIENTS OF VARIATION OF LESS THAN 10% USING A DEDICATED, INEXPENSIVE, AND SIMPLE FLUORESCENCE POLARIZATION INSTRUMENT SUITABLE FORUSE IN THE DOCTOR'S OFFICE. NO PHYSICAL SEPARATION OR PRETREATMENT OF SERA IS REQUIRED. SUCCESSFUL COMPLETION OF THESE GOALS WILL HELP SATISFY THE NEED FOR NON-HOSPITAL DRUGMONITORING FOR THE INCREASING POPULATION OF OLDER AMERICANS.

Principal Investigator:

Dr paul t nix
PRINCIPAL INVESTIGATOR
2019729375

Business Contact:

Small Business Information at Submission:

Princeton Separations Inc
37 Nottingham Road Englishtown, NJ 07726

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No