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A New Generation of Anti-Viral Vaccines for Aquaculture Using Nanotechnology

Award Information

Agency:
Department of Commerce
Branch:
N/A
Award ID:
62009
Program Year/Program:
2004 / SBIR
Agency Tracking Number:
2003-70
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
ProFishent, Inc.
17806 NE 26TH ST Redmond, WA 98052-5848
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2004
Title: A New Generation of Anti-Viral Vaccines for Aquaculture Using Nanotechnology
Agency: DOC
Contract: DG133R-04-CN-0160
Award Amount: $197,855.00
 

Abstract:

Although companies based outside the U.S. have tested and, in some cases, sold basic anti-viral vaccines to aquaculture producers, practicing veterinarians and virologists have been unimpressed by their extremely limited effectiveness (J. Mullins, pers. comm. 2002; J. Winton, pers. comm. 2004). The consensus is that new approaches are urgently needed to develop viral vaccines that do not rely on DNA technology. ProFishent will apply advances in nanotechnology to the design and construction of efficacious immersion and injection vaccines to prevent mortalities from viruses and, potentially, other intracellular pathogens. Proprietary nanoparticles will be combined with model viruses (ISAV and IHNV) to create potent immunostimulatory complexes. Vaccine prototypes will be optimized and compared to traditional formulations for their ability to stimulate immunity and to protect rainbow trout and Atlantic salmon from laboratory challenges with live pathogens. Fluorescent, antigen-coated particles will also be used to observe the effect of size on uptake and transport by the immune system.

Principal Investigator:

David B. Powell
VP, R&D
4258839896
davidp@profishent.com

Business Contact:

Roger C. Palm
President
4258839896
rogerp@profishent.com
Small Business Information at Submission:

ProFishent, Inc.
17306 NE 26th Street Redmond, WA 98052

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No