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Company Information:

Name: Proteins International Inc
Address: 1858 Star Batt Dr
Rochester Hills, MI 48309
Located in HUBZone: No
Woman-Owned: No
Minority-Owned: No
URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $295,968.00 6
SBIR Phase II $932,000.00 2

Award List:

TARGETING OF UROKINASE TO FIBRIN CLOTS

Award Year / Program / Phase: 1983 / SBIR / Phase I
Agency: HHS
Principal Investigator: Cynthia Sevilla
Award Amount: $45,968.00

TARGETING OF UROKINASE TO FIBRIN CLOTS

Award Year / Program / Phase: 1985 / SBIR / Phase II
Agency: HHS
Principal Investigator: Cynthia Sevilla
Award Amount: $500,000.00
Abstract:
The long-term objective of this project is the development and characterization of effective clot-dissolving therapy and, in particular, the study of a conjugate between human urokinase and a monoclonal antibody specific for human fibrin. this complex would allow for enhanced plasminogen activation… More

CELLULAR COMPONENTS OF THE IMMUNE SYSTEM, INCLUDING CYTOTOXIC T CELLS, MACROPHAGES, AND NATURAL KILLER CELLS, ARE CAPABLE OF THE DIRECT DESTRUCTION OF A VARIETY OF TARGETCELLS INCLUDING ALLOGENIC CELLS AND VIRUS-INFECTED OR MALIGNANT CELLS WITHIN THE

Award Year / Program / Phase: 1986 / SBIR / Phase I
Agency: HHS
Principal Investigator: Norma h mahle , PRINCIPAL INVESTIGATOR
Award Amount: $50,000.00
Abstract:
Cellular components of the immune system, including cytotoxic t cells, macrophages, and natural killer cells, are capable of the direct destruction of a variety of targetcells including allogenic cells and virus-infected or malignant cells within the host individual. research on these cellular… More

IMMUNOASSAY FOR HUMAN PROGESTERONE RECEPTOR

Award Year / Program / Phase: 1987 / SBIR / Phase I
Agency: HHS
Principal Investigator: Naomi eliezer phd
Award Amount: $50,000.00
Abstract:
Progesterone receptor is one of a group of steroid hormone receptors that has been shown to have important regulatory effects in mammary and other target tissues. the qualitative and quantitative determination of progesterone receptor is useful in the therapeutic management of breast cancer.… More

IMMUNOASSAYS FOR MUTAGENIC AND CARCINOGENIC ADDUCTS IN HUMAN DNA

Award Year / Program / Phase: 1987 / SBIR / Phase I
Agency: HHS
Principal Investigator: Cynthia L Sevilla Phd
Award Amount: $50,000.00

TARGETING OF PLASMINOGEN ACTIVATORS IN MYOCARDIAL INFARCT

Award Year / Program / Phase: 1988 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00
Abstract:
The long-term objective of this project is the development and characterization of conjugates between plasminogen activators (urokinase, tissue plasminogen activator, single chain urokinase) and monoclonal antibodies specific for human cardiac heavy chain myosin. this type of conjugate byselectively… More

IMMUNOASSAYS FOR MUTAGENIC AND CARCINOGENIC ADDUCTS IN HUMAN DNA

Award Year / Program / Phase: 1989 / SBIR / Phase II
Agency: HHS
Principal Investigator: Cynthia L Sevilla Phd
Award Amount: $432,000.00
Abstract:
Difunctional carbonyl compounds are toxic, mutagenic, and carcinogenic and are ubiquitous contaminants of the human environment. the simplest examples of such compounds are malondialdehyde, acrolein, and methyl glyoxal. malondialdehyde is a product of lipid peroxidation and prostaglandin… More

TARGETING OF IMMUNOTOXINS TO LENS EPITHELIAL CELLS

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: HHS
Principal Investigator: Naomi Eliezer
Award Amount: $50,000.00
Abstract:
A major problem in the treatment of cataracts by extracapsular lens replacement is the subsequent loss of vision due to secondary cataract formation. up to 50 percent of these patients may develop secondary cataracts. the major cause of this problem is a regrowth of lens epithelial cells that cannot… More