IMMUNOASSAY FOR HUMAN PROGESTERONE RECEPTOR

Award Information

Agency: Department of Health and Human Services	Branch: N/A	Award ID: 7205	Program Year/Program: 1987 / SBIR
Agency Tracking Number: 7205	Solicitation Year: N/A	Solicitation Topic Code: N/A	Solicitation Number: N/A

Small Business Information: Proteins International Inc
1858 Star Batt Dr Rochester Hills, MI 48309
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Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No

Phase 1: Fiscal Year: 1987

Title: IMMUNOASSAY FOR HUMAN PROGESTERONE RECEPTOR

Agency: HHS

Contract: N/A

Award Amount: $50,000.00

Abstract:
PROGESTERONE RECEPTOR IS ONE OF A GROUP OF STEROID HORMONE RECEPTORS THAT HAS BEEN SHOWN TO HAVE IMPORTANT REGULATORY EFFECTS IN MAMMARY AND OTHER TARGET TISSUES. THE QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROGESTERONE RECEPTOR IS USEFUL IN THE THERAPEUTIC MANAGEMENT OF BREAST CANCER. CURRENTLY, AVAILABLE ASSAYS FOR PROGESTERONE RECEPTOR HAVE DRAWBACKS THAT MAKE THEM DIFFICULT TO USE IN MOST CLINICAL LABORATORIES. THE MAJOR LONG-TERM GOALS OF THIS PROPOSAL ARE THE DEVELOPMENT OF A SENSITIVE, RELIABLE, ENZYME-LINKED IMMUNOASSAY FOR PROGESTERONE RECEPTOR, THE PRODUCTION OF MONOCLONAL ANTIBODIES CAPABLE OF DISTINGUISHING AMONG THE VARIOUS FORMS OF THE RECEPTOR, AND THE ISOLATION OF PURIFIEDHUMAN PROGESTERONE RECEPTOR USING AN IMMUNOAFFINITY RESIN PREPARED WITH ONE OF THE ABOVE MONOCLONAL ANTIBODIES.

Principal Investigator:
Naomi eliezer phd
3138521067

Business Contact:

Small Business Information at Submission:

Proteins International
1858 Star Batt Drive Rochester, MI 48063

EIN/Tax ID:

DUNS: N/A

Number of Employees: N/A

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No