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HIGH-RESOLUTION, TWO-DIMENSIONAL ELECTROPHORESIS CONSTITUTESTHE MOST POWERFUL…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4949
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
4949
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
PROTEUS TECHNOLOGIES, LLC
25 Gassaway Lane, Suite 201 Edgewater, MD 21037
View profile »
Woman-Owned: Yes
Minority-Owned: Yes
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1986
Title: HIGH-RESOLUTION, TWO-DIMENSIONAL ELECTROPHORESIS CONSTITUTESTHE MOST POWERFUL TOOL AVAILABLE FOR THE COMPREHENSIVE ANALYSIS OF COMPLEX PROTEIN MIXTURES.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

HIGH-RESOLUTION, TWO-DIMENSIONAL ELECTROPHORESIS CONSTITUTESTHE MOST POWERFUL TOOL AVAILABLE FOR THE COMPREHENSIVE ANALYSIS OF COMPLEX PROTEIN MIXTURES. THE TECHNIQUE HAS PROVEN EXTREMELY USEFUL IN A VARIETY OF AREAS, INCLUDING COMPARISON OF CELL TYPES, COMPARISON OF SPECIES, ANALYSIS OFDIFFERENTIATION, AND THE SEARCH FOR GENETIC VARIANTS. IN MANY APPLICATIONS, IT IS NECESSARY TO EXAMINE MODERATELY LARGE NUMBERS OF SAMPLES UNDER CONDITIONS THAT PROVIDE VERY HIGH ANALYTICAL REPRODUCIBILITY. SUCH REPRODUCIBILITY COULDBEST BE ACHIEVED USING AUTOMATED SYSTEMS FOR THE PRODUCTION OF BOTH FIRST- AND SECOND-DIMENSION GELS. THIS PROJECT DEALS WITH THE DEVELOPMENT OF A MICROCOMPUTER-CONTROLLED PUMPING DEVICE AND ASSOCIATED GEL-FORMING HARDWARE FOR THE PURPOSE OF PRODUCING LARGE NUMBERS OF VERY REPRODUCIBLE SDS ACRYLAMIDE GRADIENT SLAB GELS. THIS DEVICE CAN MAKE A MAJORCONTRIBUTION TOWARDS STANDARDIZING THE 2-D ELECTROPHORETIC TECHNIQUE, AND THUS FACILITATE THE CONSTRUCTION AND USE OF COMPREHENSIVE PROTEIN INDEXES.

Principal Investigator:

Norman leigh anderson
PRINCIPAL INVESTIGATOR
3018812600

Business Contact:

Small Business Information at Submission:

Proteus Technologies Inc
12301 Parklawn Drive Rockville, MD 20852

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No