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NEW RECORDING MEDIA FOR AN AUTOMATED GENOME MAPPING SYSTEM

Award Information

Agency:
Department of Energy
Branch:
N/A
Award ID:
10812
Program Year/Program:
1989 / SBIR
Agency Tracking Number:
10812
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Quantix Corp
2 Research Court Rockville, MD 20850
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1989
Title: NEW RECORDING MEDIA FOR AN AUTOMATED GENOME MAPPING SYSTEM
Agency: DOE
Contract: N/A
Award Amount: $49,766.00
 

Abstract:

PRESENT TECHNIQUES FOR OBTAINING INFORMATION FROM SEQUENCED ELECTROPHORESIS GELS RELY HEAVILY ON X-RAY FILM AS THE RECORDING MEDIUM. SUCH FILM SUFFERS FROM LIMITED DYNAMIC RANGE, NONLINEAR RESPONSIVITY, AND TIME-CONSUMING DEVELOPMENT TECHNIQUES. THIS PROJECT INVOLVES NEW RECORDINGMEDIA FOR AN AUTOMATED GENOME MAPPING SYSTEM. THE MEDIA AREDIFFERENT FORMULATIONS OF PROPRIETARY ELECTRON TRAPPING MATERIALS THAT HAVE THE CAPABILITY OF RECORDING BETA PARTICLE EVENTS AND EVENTS PRODUCED BY RELATIVELY SHORT-WAVEVISIBLE LIGHT. CONSEQUENTLY, THE PRESENCE OF RADIOACTIVELY TAGGED AND DYE-TAGGED DNA FRAGMENTS CAN BE RECORDED AND EVENT INFORMATION INTEGRATED. IN PHASE I DETECTOR PLANES WILL BE FABRICATED EMPLOYING ELECTRON TRAPPING PHOSPHORS. THE DETECTOR PLANES WILL THEN BE EVALUATED FOR DYNAMIC RANGE, LINEARITY OF RESPONSE TO EITHER BET RADIATION OR VISIBLE LIGHT, RESOLUTION CAPABILITY, AND RESPONSE TIME. PATTERNS OF BETA RADIATION AND LIGHT WILL BE RECORDED IN THEDETECTOR PLANES AND THEN READ OUT WITH AN X-Y SCANNING SYSTEM. THE SCANNING APPARATUS WILL BE EVALUATED TO DETERMINE THE REQUIREMENTS FOR SCANNING LARGE AREAS.

Principal Investigator:

Dr George M Storti
Principal Investigator
3012582701

Business Contact:

Small Business Information at Submission:

Quantex Corp
2 Research Ct Rockville, MD 20850

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No