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Company Information:

Company Name: REPLIGEN CORPORATION
City: WALTHAM
State: MA
Zip+4: 02453
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: (781) 250-0111

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $576,683.00 8
SBIR Phase II $1,228,999.00 2

Award List:

LIGNINOLYTIC ENZYMES APPLIED TO KRAFT LIGNIN AND LIGNOSULFONATE UTILIZATION

Award Year / Program / Phase: 1985 / SBIR / Phase I
Agency: DOE
Principal Investigator: Dr. Roberta Farrell , Principal Investigator
Award Amount: $50,000.00

LIGNINOLYTIC ENZYMES APPLIED TO KRAFT LIGNIN AND LIGNOSULFONATE UTILIZATION

Award Year / Program / Phase: 1986 / SBIR / Phase II
Agency: DOE
Principal Investigator: Dr. Roberta Farrell , Principal Investigator
Award Amount: $479,000.00
Abstract:
Lignin, a complex organic polymer and one of the earth's most abundant molecules, is now a low-value by-product of wood pulp processing. the major lignin by-products, kraft lignin, and lignosulfonates, could be more useful, howvere, if their chemical structure could be specifically altered. by using… More

GENERATION OF PF4 POLYETHYLENE GLYCOL CONJUGATES

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Lai, Chee K , Principal Investigator
Award Amount: $27,274.00
Abstract:
Angiogenesis is a complex process involving the proliferation, migration, and precise three dimensional alignment of endothelial cells. a wide range of disease processes including solid tumor growth, diabetic retinopathy, inflammatory arthritis, and psoriasis are associated with aberrant… More

ANTIBODY HETEROCONJUGATES FOR TREATMENT OF SIV INFECTION

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Higgins, Paul J , Principal Investigator
Award Amount: $49,984.00
Abstract:
The goal of this project is to generate and characterize a bispecific heteroconjugate antibody capable of inducing the cytolysis of siv-infected cells. the approach in phase i study will entail conjugating an anti-cd3 monoclonal antibody with an antibody specific for recombinant siv envelope… More

SUPPOSITORIES FOR RAPID ANTI-EPILEPTIC DIAZEPAM DELIVERY

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: , Principal Invetsigator
Award Amount: $49,861.00

Development of Chemokines for Myeloprotection

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: HHS
Principal Investigator: Thomas Daly
Award Amount: $99,998.00
Abstract:
We will develop a myelostatic agent to protect human hematopoietic precursor cells from the destrucchemotherapeutic agents currently used in the treatment of tumors. We propose that protection of preinhibition of growth during cancer treatment would reduce the toxicity associated with standard… More

Development of Chemokines for Myeloprotection

Award Year / Program / Phase: 1998 / SBIR / Phase II
Agency: HHS
Principal Investigator: Thomas Daly
Award Amount: $749,999.00
Abstract:
We will develop a myelostatic agent to protect human hematopoietic precursor cells from the destrucchemotherapeutic agents currently used in the treatment of tumors. We propose that protection of preinhibition of growth during cancer treatment would reduce the toxicity associated with standard… More

Development of a Heparinoid Affinity Matrix by Combinatorial Chemistry

Award Year / Program / Phase: 1999 / SBIR / Phase I
Agency: NSF
Principal Investigator: Jundong Zhang
Award Amount: $99,906.00

HEPARANASE INHIBITORS FOR USE IN METASTATIC DISEASES

Award Year / Program / Phase: 1999 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ariane E. Marolewski
Award Amount: $99,660.00
Abstract:
Not Available Oman Moments, Inc. will conduct a Phase 1 trade study to determine the best approach for providing both day and night imaging of ground targets from a supersonic missile. The objective is to develop a practical window system that permits both visible and IR operation in the missile's… More

IMPROVED SECRETIN ANALOGS FOR THE TREATMENT OF AUTISM

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Richard Boismenu
Award Amount: $100,000.00
Abstract:
Non invasive MRI evaluation of the carotid artery wall lumen and blood flow patterns is hampered by the lack of a comprehensive and anatomically correct commercially available flow phantom. The objective of this project is to develop an advanced artificial carotid artery flow phantom for use in… More