A major concern in environmental and occupational air pollution is the hazard posed by suspected carcinogens. whereas most previous research has focused on concentrations or bioassays of specific chemical agents, the proposed development of the ""c-probe'' direct passive monitor offers a greatly… More

As part of an overall effort to develop an amplifying alarm monitor for nerve agents, a program is proposed for the verification of a biochemical system to mimic the physiological receptor mechanisms for nerve agent toxicity, and to convert the chemical and biochemical information into an output… More

Soil contamination by toxic wastes has destroyed significantvaluable land acreage. recent development of soil remediation technologies permits reclamation of much lost land for productive uses. the proposed research will investigate revegetation methods which will complete the soil detoxification… More

A proposed high temperature thermocouple calibrator for use in flowing gas streams comprises three subsystems: (a) a hot gas generator using a plasma generator or flat flame burner as the heat source; (b) a laser doppler velocimetry system for measuring velocity components in the neighborhood of the… More

Coupling a biological probe to a microelectrode offers greatpotential for direct, rapid, sensitive and specific detection of a wide range of toxins, viruses, and biological agents. the proposed imminochemically coupled electrode (icm) offers significant promise for broad-spectrum and sensitive… More

This research and development effort is aimed toward the validation and use of a portable biochemical detector ("c-probe") as an indicator for human exposures to carcinogenic chemical agents in the field. during phase i, c-probe responses to test agents will be compared with in vitro and in vivo… More

Development of an amplifying chemical agent detector, incorporating a modular approach to sensing of nerve agents and other chemicals of military interest, is proposed. the three modules: (1) a dynamic trigger which responds to the chemical agent of interest; (2) a bioamplifier which contains the… More

Thin film membrane-based sensors and components show promise for a variety of government and commercial uses. they offer potential for very high (up to 10(12)) amplification gain, dime-sized dimensions, with specificity as desired for biological processes and agents. examples might include microbial… More