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TC-99M-LABELED CHEMOTACTIC PEPTIDES FOR ABSCESS IMAGING

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
18971
Program Year/Program:
1992 / SBIR
Agency Tracking Number:
18971
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Rhomed, Inc.
C/O PALATIN TECHNOLOGIES, INC. Princeton, NJ 08540
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1992
Title: TC-99M-LABELED CHEMOTACTIC PEPTIDES FOR ABSCESS IMAGING
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

FORMULATED CHEMOTACTIC PEPTIDES, WITH ENDOGENOUS TC-99M BINDING SITES, WILL BE DEVELOPED FOR USE IN LOCALIZING ABSCESSES, INFLAMMATIONS, AND INFECTIONS. THE PEPTIDES ARE DESIGNED TO HAVE THE BIOLOGICAL FUNCTION LOCATED AT ONE END OF THE MOLECULE, AND THE TC-99M BINDING SITE AT THE OTHER END OF THE MOLECULE. IN PHASE I THE CHEMOTACTIC PEPTIDE ANALOGS WILL BE FORMULATED IN SINGLE-STEP, DIRECT LABELING KITS, AND USED IN ANIMAL STUDIES TO LOCALIZE INFECTIONS AND INFLAMMATIONS. INITIAL STUDIES WILL INCLUDE ANALYSIS OF LABELING EFFICIENCY AND DEFINITION OF OPTIMAL LABELING CONDITIONS, AND BINDING OF TC-99M-LABELED FORMYL PEPTIDES TO LYPHOCYTES. IN PHASE II, COMPARATIVE LOCALIZATION STUDIES WILL BE CONDUCTED, USING IN-111-OXINE-LABELED LYMPHOCYTES AND TC-99M-HUMAN GAMMA GLOBULIN AS REFERENCE MATERIALS.

Principal Investigator:

Paul O Zamora
5053447200

Business Contact:

Small Business Information at Submission:

Rhomed Inc
4216 Balloon Park Road Ne Albuquerque, NM 87109

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No