USA flag logo/image

An Official Website of the United States Government

SBIR Phase I: Development of Resonant Waveguide-Grating Elements for High…

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
79592
Program Year/Program:
2006 / SBIR
Agency Tracking Number:
0539519
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
RSI
202 East Border Street Arlington, TX 76010
View profile »
Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2006
Title: SBIR Phase I: Development of Resonant Waveguide-Grating Elements for High Throughput Screening of Proteins
Agency: NSF
Contract: 0539519
Award Amount: $100,000.00
 

Abstract:

This Small Business Innovative Research Phase I project will develop a highly sensitive optical sensor system for use in high-throughput screening applications. The heart of the proposed sensor system is a periodic dielectric waveguide in which resonant leaky modes are excited by an incident optical wave. Attachment of biomolecular layers on the sensor surface yields spectral shifts that are measured to identify the binding event with high sensitivity and specificity without fluorescent tags. Both major polarization states have independent resonant peaks to accurately sense a biomaterial binding event. This feature enables the capability to distinguish between average thickness changes and average density changes occurring at the sensor surface. High resolution (from narrow, well defined resonance peaks) and high sensitivities permit a high probability of accurately detecting an event. The new class of bio- and chemical sensors proposed will provide benefits to society due to their utility in drug development, genomics, environmental monitoring, and homeland security. The fact that they operate without chemical tags permits observation and study of unperturbed biochemical processes in real-time, and no foreign substance are introduced. This will result in a deeper understanding of chemical and bio-chemical molecular processes and may lead to significant advances in drug and chemical development.

Principal Investigator:

Debra Wawro
Ms
8173008287
wawro@resonantsensors.com

Business Contact:

Debra Wawro
Ms
8173008297
wawro@resonantsensors.com
Small Business Information at Submission:

RSI
202 East Border Street Arlington, TX 76010

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No