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Company Information:

Company Name: RULES-BASED MEDICINE, INC.
City: AUSTIN
State: TX
Zip+4: 78759-3549
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $2,258,456.00 8
SBIR Phase II $1,546,728.00 2
STTR Phase I $99,608.00 1
STTR Phase II $750,000.00 1

Award List:

Rapid Assessment of Individual Soldier Operational Readiness

Award Year / Program / Phase: 2004 / STTR / Phase I
Agency / Branch: DOD / ARMY
Research Institution: Lawrence Livermore National Labator
Principal Investigator: James Mapes, Chief Scientific Officer
Award Amount: $99,608.00
RI Contact: Richard Langlois
Abstract:
It is important to develop a hierarchical series of molecular biomarkers for the rapid assessment of a soldier's physiological and operational readiness. Stress factors play an important role in combat related illnesses among troops. Studies of Gulf War Syndrome and other combat related disorders… More

Biomarker Profiles for Predicting Stroke Using Stroke-Prone Rats as a Model

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: James P. Mapes
Award Amount: $99,605.00
Abstract:
DESCRIPTION (provided by applicant): Stroke is the third leading cause of death and is a leading cause of serious, long-term disability in the United States. A new or recurrent stroke is suffered by ~ 700,000 Americans each year. An estimated 57.9 billion dollars will be spent to cover the… More

Rapid Assessment of Individual Soldier Operational Readiness

Award Year / Program / Phase: 2007 / STTR / Phase II
Agency / Branch: DOD / ARMY
Research Institution: LAWRENCE LIVERMORE NATIONAL LABORAT
Principal Investigator: James Mapes
Award Amount: $750,000.00
RI Contact: Kenneth W. Turteltaub
Abstract:
Deployed troops experience a wide variety of performance-degrading stressors, including fatigue, depressed nutrition, sustained physical activity, fear, vaccinations, environmental chemicals, and unusual pathogens. The goal of this program is to develop a hierarchical series of molecular biomarkers… More

Biomarker Profiles for Early Diagnosis of Sepsis in Neonates

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: James P. Mapes
Award Amount: $99,426.00
Abstract:
DESCRIPTION (provided by applicant): Sepsis is a frequent and serious problem in neonatal intensive care units, particularly in very low birth weight (VLBW) infants. Over 20% of all VLBW infants experience one or more episodes of late-onset sepsis. Unfortu nately, diagnosis by blood culture is… More

SBIR TOPIC 238 - DEVELOPMENT OF CLINICAL AUTOMATED MULTIPLEX AFFINITY CAPTURE TEC

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Mapes James
Award Amount: $146,877.00

Biomarker Profiles for Carbon Monoxide Poisoning

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator: James P. Mapes
Award Amount: $100,000.00
Abstract:
DESCRIPTION (provided by applicant): Carbon monoxide (CO) is the leading agent of injury and death by poisoning worldwide. Diagnosis of CO poisoning can be delayed by non-specific symptoms, thus preventing early treatment and identification of the contamin ation source. Survivors are faced with… More

Biomarker Profiles for Early Diagnosis of Sepsis in Neonates

Award Year / Program / Phase: 2008 / SBIR / Phase II
Agency: HHS
Principal Investigator: James P. Mapes – (512) 835-8026
Award Amount: $711,006.00
Abstract:
DESCRIPTION (provided by applicant): Sepsis is a frequent and serious problem in neonatal intensive care units, particularly in very low birth weight (VLBW) infants. Over 20% of all VLBW infants experience one or more episodes of late-onset sepsis. Unfortu nately, diagnosis by blood culture is… More

SBIR TOPIC 238 - DEVELOPMENT OF CLINICAL AUTOMATED MULTIPLEX AFFINITY CAPTURE TEC

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator: Huiping Li
Award Amount: $1,458,408.00
Abstract:
Applied Media Analysis, Inc (AMA) proposes to collaborate with the George Washington University Weight Management Program and Peaksware LLC to demonstrate the technical feasibility of MobileVision DietMonitor, a software-based solution which uses existing camera-enabled smart phones to provide… More

IMPROVEMENT OF A PROMISING MAP FOR OVARIAN CANCER

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator: Laurie Stephen
Award Amount: $149,875.00
Abstract:
Mortality from ovarian cancer (OvCa), the deadliest gynecological cancer in the United States has declined little for -50 years. When treated early, the 5-year survival rate is 93%, but only 19% are detected at stage I. Early-detection remains a critical, unmet medical need. Single diagnostic… More

Identification of a Multi-Analyte Profile for Primary Hyperoxaluria

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: James P. Mapes
Award Amount: $104,265.00
Abstract:
DESCRIPTION (provided by applicant): Primary hyperoxaluria, type 1 (PH1) is a rare, monogenic disorder in which a mutation in the AGXT gene leads to overproduction of oxalate by the liver, resulting in widespread deposition of calcium oxalate in the kidney s and other organs. Unfortunately, PH1… More

Biomarker Profiles for Prediction and Diagnosis of Post-Transplant Renal Injury

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: James P. Mapes
Award Amount: $100,000.00
Abstract:
DESCRIPTION (provided by applicant): Post-transplant renal injury is a mechanistically complex process that leads to progressive, chronic renal insufficiency and constitutes a major clinical barrier to the short- and long-term success of all organ transpla nts. There is a strong need for… More

Identification of a Multi-Analyte Profile for Primary Hyperoxaluria

Award Year / Program / Phase: 2011 / SBIR / Phase II
Agency: HHS
Principal Investigator: James P. Mapes – 512-835-8026
Award Amount: $835,722.00
Abstract:
DESCRIPTION (provided by applicant): Primary hyperoxaluria, type 1 (PH1) is a rare, monogenic disorder in which a mutation in the AGXT gene leads to overproduction of oxalate by the liver, resulting in widespread deposition of calcium oxalate in the kidneys and other organs. Unfortunately, PH1… More