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Rapid Assessment of Individual Soldier Operational Readiness

Award Information

Department of Defense
Award ID:
Program Year/Program:
2004 / STTR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
3300 Duval Rd AUSTIN, TX 78759-3549
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2004
Title: Rapid Assessment of Individual Soldier Operational Readiness
Agency / Branch: DOD / ARMY
Contract: W911SR-04-P-0095
Award Amount: $99,608.00


It is important to develop a hierarchical series of molecular biomarkers for the rapid assessment of a soldier's physiological and operational readiness. Stress factors play an important role in combat related illnesses among troops. Studies of Gulf War Syndrome and other combat related disorders provide evidence that a wide range of stressors can degrade performance (e.g. fatigue, nutrition, sustained physical activity, fear, sustained attention, vaccinations, environmental chemicals, and unusual pathogens). Clearly, no single molecular marker, or small group of markers, will be able to accurately report the status of this wide variety of stress mechanisms. Rules-Based Medicine (RBM) has developed fluorescent microsphere array approach to perform Multi-Analyte Profiles (x-MAP) in blood. This technology is well suited for screening large numbers of markers in parallel to identify stress profiles. The research work on stress profiles facilitates comparison between stress responses and disease mechanisms. This should also increase the understanding and robustness of readiness profiles. Lawrence Livermore National Laboratory (LLNL) has a number of ongoing collaborations with RBM to develop and apply multiplex immunoassays to the study of infectious diseases. Thus, RBM and LLNL are uniquely qualified to perform high-throughput analyses of genomic, proteomic and other biomarkers, and to facilitate application of these approaches by those responsible for assessing troop training and readiness.

Principal Investigator:

James Mapes
Chief Scientific Officer

Business Contact:

James Mapes
Chief Scientific Officer
Small Business Information at Submission:

3300 Duval Rd, Suite 110 Austin, TX 78759

EIN/Tax ID: 223860791
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
Lawrence Livermore National Labator
7000 East Ave.,
Livermore, CA 94550
Contact: Richard Langlois
Contact Phone: (925) 422-5616
RI Type: Federally funded R&D center (FFRDC)