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Diode Pumped Laser for 2 Proton Fluorescence Microscope

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
29678
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
29678
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
SCHWARTZ ELECTRO-OPTICS, INC.
3404 N. Orange Blossom Trail Orlando, FL 32804
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1995
Title: Diode Pumped Laser for 2 Proton Fluorescence Microscope
Agency: HHS
Contract: 1 R43 RR10762-01,
Award Amount: $100,000.00
 

Abstract:

Recent advances in ultrafast, solid-state, near-infrared laser sources have led to the developmentlaser-based techniques in scientific instrumentation, including demonstrations of high-resolution, tof biophysical specimens using two photonexcitation fluorescence (TPF) laser scanning microscopy. Thcombines the spatial imaging properties of the laser scanning microscope (LSM) with TPF from naturalfluorphores, such as nicotinamide adenine dinucleotide (NADH), or staining dyes to study specimens aAn ultrafast laser source intended for TPF laser scanning microscopy in biophysics and biology shoul670 nm to 780 nm, provide sub-100 fs duration pulses at 100 MHz repetition rates, and have an averagKey development goals should be low cost (both capital and operating), small size, reliability, effioperation. In this effort we will address these goals with the development of a frequency-doubled, slaser. TPF laser scanning microscopy will be demonstrated using this source, with emphasis on excitaNADH at 680 nm with sub-micron spatial resolution.

Principal Investigator:

David Welford
40798

Business Contact:

Small Business Information at Submission:

Schwartz Electro-optics, Inc.
3404 N Orange Blossom Trail Orlando, FL 32804

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No