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IN-VIVO RESONANT-GAMMA DETECTION/IMAGING OF N AND CA

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
16533
Program Year/Program:
1992 / SBIR
Agency Tracking Number:
16533
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
SCIENCE RESEARCH LABORATORY INC
15 Ward Street Somerville, MA -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1992
Title: IN-VIVO RESONANT-GAMMA DETECTION/IMAGING OF N AND CA
Agency: HHS
Contract: N/A
Award Amount: $499,820.00
 

Abstract:

RESONANT GAMMA ABSORPTION WILL BE USED FOR IN-VIVO DETECTION AND IMAGING OF BODY NITROGEN AND CALCIUM. TWO MAJOR APPLICATIONS ARE NUTRITIONAL ASSESSMENT OF CRITICALLY ILL PATIENTS AND OSTEOPOROSIS SCREENING. REQUIRED RADIATION DOSES FOR WHOLE- BODY MEASUREMENTS ARE 3-4 ORDERS OF MAGNITUDE LOWER THAN MAY BE DONE BY PRESENT TECHNIQUES. A NOVEL, COMPACT ELECTROSTATIC PROTON ACCELERATOR WILL PRODUCE A 1 MA PROTON BEAM OF ENERGY 1.75 MEV (FOR NITROGEN DETECTION) OR 2.04 MEV (FOR CA DETECTION). PROTONS CAPTURED IN A TARGET PRODUCE GAMMA RAYS RESONANT WITH EITHER N OR CA. THE MEASURED TRANSMISSION OF THE RESONANT GAMMAS THROUGH THE BODY IS USED TO DETERMINE THE BODY CONTENT OF THESE ELEMENTS. THE TECHNIQUE REQUIRES NO RADIOACTIVE SOURCE AND A DOSE SO MODEST THAT BODY SCANS WITH 2 CM RESOLUTION ARE ENVISIONED. PHASE I IS A THEORETICAL EFFORT TO QUANTIFY THE TECHNIQUE, DESIGN AN ELECTROSTATIC ACCELERATOR, AND OPTIMIZE THE GEOMETRIC INTERFACING BETWEEN THE ACCELERATOR, TARGET AND DETECTOR SYSTEM.

Principal Investigator:

Flusberg, Allen M
Principal Investigator
6175471122

Business Contact:

1 r43 dk43556-01
Small Business Information at Submission:

Science Research Laboratory
15 Ward Street Somerville, MA 02143

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No