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Advanced Accelerator Design to Enhance Boron-Neutron-Capture Therapy

Award Information

Agency:
Department of Energy
Branch:
N/A
Award ID:
50798
Program Year/Program:
2001 / STTR
Agency Tracking Number:
DE-FG02-00ER86111
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
SCIENCE RESEARCH LABORATORY INC
15 Ward Street Somerville, MA -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2001
Title: Advanced Accelerator Design to Enhance Boron-Neutron-Capture Therapy
Agency: DOE
Contract: DE-FG02-00ER86111
Award Amount: $500,000.00
 

Abstract:

Recent clinical trials have cast doubt on the efficacy of Boron Neutron Capture Therapy (BNCT) for brain tumor treatment when low energy, reactor-generated neutron beams are used. It has been predicted that higher energy, accelerator-produced neutron beams would have an epithermal neutron spectrum that would be much more effective. Therefore, this project will design and fabricate an innovative accelerator for neutron generation based on an RF shunt-fed voltage multiplier. Phase I showed that a shunt-fed, inductively coupled accelerator is capable of clinical BNCT by demonstrating: (1) the required multi-stage voltage multiplication at high current; (2) the low voltage ripple characteristics required to support 2.5 MeV operation at high current; and (3) that the all-solid-state power supply can be successfully matched to the accelerating column, delivering the required voltage and current characteristics. Phase II will verify that a 2.5 MV, 50 mA electrostatic accelerator can be built for BNCT. The resulting energy spectrum of the produced neutrons will be optimized for BNCT trials.

Principal Investigator:

Rodney Petr
Principal Investigator

Business Contact:

Small Business Information at Submission:

Science Research Laboratory, Inc.
15 Ward Street Somerville, MA 02143

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
Lawrence Berkeley National Laboratory
University of California One Cclotron Road
Berkeley, CA 94720
RI Type: Federally funded R&D center (FFRDC)