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Development of a Novel Virus Capture System Using Positively Charged Silica…

Award Information

Agency:
Environmental Protection Agency
Branch:
N/A
Award ID:
74241
Program Year/Program:
2006 / SBIR
Agency Tracking Number:
EP-D-05-037
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Scientific Methods, Inc.
12441 Beckley St. Granger, IN 46530
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2006
Title: Development of a Novel Virus Capture System Using Positively Charged Silica Matrix
Agency: EPA
Contract: EP-D-06-086
Award Amount: $343,486.00
 

Abstract:

The Phase II goals aim to build upon the successful feasibility study completed during Phase I study and to complete the research required to commercialize the functionalized silica beads for virus detection and point-of use treatment applications. The primary Phase II objectives are aimed at developing two products: (1) a virus `capture-and-release¿ bead for use in human enteric virus and coliphage monitoring, and (2) a `capture-only¿ bead for point-of-use treatment applications. The study will focus on assessing the compatibility of eluates generated using the `capture-and-release¿ bead with downstream enumerative assays (both culture-based and molecular-based assays will be evaluated using water seeded with human enteric viruses), validation of the `capture-only¿ bead for point-of-use water treatment, and optimization of methods for commercial scale bead production (>1 kg functionalized beads per batch). Two silica formulations will be produced and validated for virus concentration and point-of-use treatment applications. The functionalized silica beads that will be synthesized during Phase II study have several commercial applications as low-cost human enteric virus and viral indications (coliphage) concentrations/detection products, and for incorporation into personal water purification devices.

Principal Investigator:

Fu-Chih Hsu
Director of Operations
5742774078
fuchih@scientificmethods.com

Business Contact:

Rebecca C. Larkin
Accounts Manager
5742774078
ruby@scientificmethods.com
Small Business Information at Submission:

Scientific Methods, Inc.
12441 Beckley St. Granger, IN 46530

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No