TUNABLE TIME-RESOLVED FLUORESCENCE MICROSCOPY

Award Information

Agency: National Science Foundation	Branch: N/A	Award ID: 14402	Program Year/Program: 1991 / SBIR
Agency Tracking Number: 14402	Solicitation Year: N/A	Solicitation Topic Code: N/A	Solicitation Number: N/A

Small Business Information: SCIENTIFIC RESEARCH ASSOC., INC.
P. O. Box 1058, 30C Hebron Avenue Glastonbury, CT 06033
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Minority-Owned: No

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Phase 1: Fiscal Year: 1991

Title: TUNABLE TIME-RESOLVED FLUORESCENCE MICROSCOPY

Agency: NSF

Contract: N/A

Award Amount: $49,947.00

Abstract:
DEVELOPMENT OF A TIME-RESOLVED FLUORESCENCE MICROSCOPY SYSTEM IS PROPOSED. THE SYSTEM WOULD EMPLOY ACOUSTOOPTIC TUNABLE FILTERS AS SPECTRAL TUNING ELEMENTS IN LIEU OF THE CONVENTIONAL INTERFERENCE FILTERS, AND A PHASE-MODULATED IMAGE DISSECTOR TUBE (OR A NANOSECOND GATED CCD) AS A DETECTOR. THE COMBINATION OF THESE TECHNOLOGIES IS EXPECTED TO RESULT IN A DRAMATIC IMPROVEMENT IN SENSITIVITY,VERSATILITY AND ANALYSIS SPEED. THE ABILITY TO PERFORM FLUORESCENCE LIFETIME MEASUREMENTS IN TWO DIMENSIONS SHOULD ENABLE MICROSCOPISTS TO QUANTITATE QUENCHING CORRECTIONS WHICH ARE NECESSARY TO RELATE MEASURED SIGNALS TO FLUOROPHORE CONCENTRATION.

Principal Investigator:
Dr. Salvador M. Fernandez
Director Of Applied Optics
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Small Business Information at Submission:

Scientific Research Associates
50 Nye Rd Po Box 1058 Glastonbury, CT 06033

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Number of Employees: N/A

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No