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TUNABLE TIME-RESOLVED FLUORESCENCE MICROSCOPY

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
14402
Program Year/Program:
1991 / SBIR
Agency Tracking Number:
14402
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
SCIENTIFIC RESEARCH ASSOC., INC.
P. O. Box 1058, 30C Hebron Avenue Glastonbury, CT 06033
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1991
Title: TUNABLE TIME-RESOLVED FLUORESCENCE MICROSCOPY
Agency: NSF
Contract: N/A
Award Amount: $49,947.00
 

Abstract:

DEVELOPMENT OF A TIME-RESOLVED FLUORESCENCE MICROSCOPY SYSTEM IS PROPOSED. THE SYSTEM WOULD EMPLOY ACOUSTOOPTIC TUNABLE FILTERS AS SPECTRAL TUNING ELEMENTS IN LIEU OF THE CONVENTIONAL INTERFERENCE FILTERS, AND A PHASE-MODULATED IMAGE DISSECTOR TUBE (OR A NANOSECOND GATED CCD) AS A DETECTOR. THE COMBINATION OF THESE TECHNOLOGIES IS EXPECTED TO RESULT IN A DRAMATIC IMPROVEMENT IN SENSITIVITY,VERSATILITY AND ANALYSIS SPEED. THE ABILITY TO PERFORM FLUORESCENCE LIFETIME MEASUREMENTS IN TWO DIMENSIONS SHOULD ENABLE MICROSCOPISTS TO QUANTITATE QUENCHING CORRECTIONS WHICH ARE NECESSARY TO RELATE MEASURED SIGNALS TO FLUOROPHORE CONCENTRATION.

Principal Investigator:

Dr. Salvador M. Fernandez
Director Of Applied Optics
0

Business Contact:

Small Business Information at Submission:

Scientific Research Associates
50 Nye Rd Po Box 1058 Glastonbury, CT 06033

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No