BIOLUMINESCENT ASSAY FOR GENE EXPRESSION ANALYSIS

Award Information

Agency: Department of Health and Human Services	Branch: N/A	Award ID: 79979	Program Year/Program: 2008 / SBIR
Agency Tracking Number: GM080037	Solicitation Year: N/A	Solicitation Topic Code: N/A	Solicitation Number: N/A

Small Business Information: SCI-TEC, INC.
10425 COGDILL RD. #300 KNOXVILLE, TN -
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Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No

Phase 2: Fiscal Year: 2008

Title: BIOLUMINESCENT ASSAY FOR GENE EXPRESSION ANALYSIS

Agency: HHS

Contract: 2R44GM080037-02

Award Amount: $728,798.00

Abstract:
DESCRIPTION (provided by applicant): The goal of this project is to develop a new highly sensitive and cost effective RNA Bioluminescent Assay (RT-qBLA) for high-throughput detection and quantification of RNA and DNA in biological samples. The assay imple ments the same detection concept known from pyrosequencing, yet expanding pyrosequencing methodology for highly sensitive and accurate quantification of RNA and DNA molecules. The proposed assay has unique sensitivity and dynamic range and is able to measu re kinetics of RNA and DNA replication in the solution in real time without long and expensive sample amplification of the real time PCR. The RT-qBLA requires less expensive reagents and equipment than real time PCR and DNA microarrays and can be used in a various commercial assays in life sciences research, drug discovery, and clinical diagnosis.

Principal Investigator:

Business Contact:

golovlev@scien-tec.com

Small Business Information at Submission:

SCI-TEC, INC.
10425 COGDILL RD. #300 KNOXVILLE, TN 37932

EIN/Tax ID: 621584121

DUNS: N/A

Number of Employees: N/A

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No