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Cryptosporidosis--A Bioluminescent Cryptosporidium Assay

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
29144
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
29144
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Sealite Sciences, Inc.
3000 N WOODS PKY, STE 200 Norcross, GA 30071
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1995
Title: Cryptosporidosis--A Bioluminescent Cryptosporidium Assay
Agency: HHS
Contract: 1 R43 AI38689-01,
Award Amount: $92,972.00
 

Abstract:

There has been a recent concern raised regarding the contamination of water supplies by CryptosporiThis was sparked by the outbreak that occurred in Milwaukee. While contamination by any microbial agCryptosporidium has received much attention, in part, because it is a problem for immunocompromisedthose with AIDS. Current methods of diagnosing cryptosporidiosis in humans is based on the detectionMore recently immunofluorescent test have provided increased sensitivity, but it is dependent on traexpensive equipment i.e., fluorescent microscope. The development of a simple, economical highly senimmunoassay for the detection and quantification of Cryptosporidium oocysts in both clinical and envthe subject of this proposal. This is to be accomplished using monoclonal antibodies specific for thproprietary bioluminescent detection system. The bioluminescent label is based on Aqualite technologphotoprotein which when conjugated with antibodies results in highly sensitive bioluminescent detectbeen successfully applied to a number of clinical assays.

Principal Investigator:

David Smith
70646

Business Contact:

Small Business Information at Submission:

Sealite Sciences, Inc.
187 Ben Burton Circle Bogart, GA 30622

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No