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High-Throughput Brain Injury Proteomic Microassay

Award Information

Agency:
Department of Defense
Branch:
Office of the Secretary of Defense
Award ID:
76634
Program Year/Program:
2005 / STTR
Agency Tracking Number:
O054-003-2024
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
SFC FLUIDICS, LLC
534 W. Research Blvd, Suite 260 FAYETTEVILLE, AR 72701-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2005
Title: High-Throughput Brain Injury Proteomic Microassay
Agency / Branch: DOD / OSD
Contract: W81XWH-05-C-0172
Award Amount: $100,000.00
 

Abstract:

SFC Fluidics in coordination with the University of Arkansas proposes to develop an immunoassay based lab-on-a-chip using the advantages of self-contained microelectrochemical detection and redox magnetohydrodynamic (MHD) microfluidics for the rapid detection of biomarkers of traumatic brain injury (TBI) from a pinprick sample of blood. The disposable cartridge will contain all of the reagents necessary to complete the assay and will move the components of the assay along preprogrammed paths. All that the user will need to do is inject a known quantity of blood serum from a patient, push a button and wait ~30 min for a digital readout of results. The instrument will be designed to be sturdy and compact as would be necessary for diagnosing a soldier in the field. In Phase I we will demonstrate the microelectrochemical-based assay platform to simultaneously detect two TBI biomarkers in blood serum for which monoclonal antibodies are commercially available. Phase I will also focus on the manipulation of the immunoassay components in a redox magnetohydrodynamic (MHD) based microfluidic network to show feasibility. This microelectrochemical assay/MHD microfluidic cartridge can be expanded later in Phase II to incorporate many other biomarkers for TBI and allow for portability and complete automation.

Principal Investigator:

Prabhu Arumugam
Senior Engineer
4795712592
prabhu.arumugam@sfc-fluidics.com

Business Contact:

Mark Wagstaff
Vice President
4795712592
mwagstaff@virtual-incubation.com
Small Business Information at Submission:

Sfc Fluidics, Llc
535 W. Research Blvd., Suite 135, M/S 400 Fayetteville, AR 72701

EIN/Tax ID: 113682226
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
UNIV. OF ARKANSAS
Research and Sponsored Program, 120 Ozark Hall
Fayetteville, AR 72701
Contact: Rosemary Ruff
Contact Phone: (479) 575-3845
RI Type: Nonprofit college or university