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Company Information:

Company Name: SILOAM BIOSCIENCES
City: CINCINNATI
State: OH
Zip+4: 45240
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $809,570.00 7
SBIR Phase II $2,098,331.00 3

Award List:

SBIR Phase I: A Smart Disposable Plastic Lab-On-A-Chip for Point-Of-Care Monitoring of Cardiac Markers

Award Year / Program / Phase: 2004 / SBIR / Phase I
Agency: NSF
Principal Investigator: Jae Lee, PI
Award Amount: $99,450.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project proposes to develop a rapid and reliable point-of-care system for detection of cardiovascular disease and myocardial infarction biomarkers. The biochip proposed in this work could significantly reduce the detection time while… More

A Handheld Monitoring System For Biomarkers Of Response From Blood

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Jae Y. Lee, CEO, Managing Member
Award Amount: $70,000.00
Abstract:
The goal of this SBIR Phase I effort is to demonstrate proof-of-concept for a functional handheld system to monitor biomarkers or response. Specifically, during the Phase I effort we will demonstrate a disposable biochip, which can be used as a part of the handheld system, for simultaneous… More

Disposable Saliva biochip for Breast Cancer Biomarkers

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: HHS
Principal Investigator: Jae Y. Lee
Award Amount: $99,640.00
Abstract:
DESCRIPTION (provided by applicant): The objective of this Phase I SBIR proposal is the development of a non-invasive, disposable biochip for the analysis of a panel of breast cancer biomarkers (c-erbB-2 and CA15-3) from saliva. The disposable biochip uses fluorescent immunoassay on a… More

A Handheld Monitoring System For Biomarkers Of Response From Blood

Award Year / Program / Phase: 2006 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Jae Y. Lee, CEO, Managing Member
Award Amount: $728,142.00
Abstract:
The goal of this SBIR Phase II effort is the development of a prototype system for point-of-care monitoring of biomarkers of exposure. Two biochips will be developed for: (a) Cholinesterase panel - monitoring Acetylcholinesterase and Butyrylcholinesterase activities as biomarkers of exposure to… More

SBIR Phase I: Rapid Toxic Alcohols Detection Using On-Chip Biosensor Array for Emergency Care

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: NSF
Principal Investigator: Jae Y. Lee, Dr
Award Amount: $97,196.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I Project is targeted towards the development of a biosensor array for point-of-care (POCT) detection of toxic alcohols. The sensor arrays would eventually be a part of a fully-disposable, plastic biochip which would be the first ever POCT system… More

High-Throughput Plastic Microfabrication Technologies for Smart Lab-on-a-Chips

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Aniruddha P. Puntambekar
Award Amount: $94,714.00
Abstract:
DESCRIPTION (provided by applicant): The objective of this revised fast-track effort is the development of reliable, high-throughput microfabrication techniques for production of lab-on-a-chip for Point-of-Care Testing (POCT) applications. The proposed fab rication processes will significantly… More

High-Throughput Plastic Microfabrication Technologies for Smart Lab-on-a-Chips

Award Year / Program / Phase: 2008 / SBIR / Phase II
Agency: HHS
Principal Investigator: Aniruddha P. Puntambekar
Award Amount: $372,935.00
Abstract:
DESCRIPTION (provided by applicant): The objective of this revised fast-track effort is the development of reliable, high-throughput microfabrication techniques for production of lab-on-a-chip for Point-of-Care Testing (POCT) applications. The proposed fab rication processes will significantly… More

RAPID QUANTITATIVE POINT OF CARE TEST FOR NICOTINE METABOLITE

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Aniruddha Puntambekar
Award Amount: $150,000.00
Abstract:
The goal of this fast-track SBIR project is to develop the first ever, point-if-care test (POCT) to determine the ratio of nicotine metabolites; 3-hydroxycotinine/cotinine (3HC/COT). This test can be used by physicians to adapt nicotine replacement therapies/non-nicotine drugs for smoking cessation… More

TAS::75 0893::TAS RAPID QUANTITATIVE POINT OF CARE TEST FOR NICOTINE METABOLITE RATIO, SILOAM BIOSCIENCES, INC. CINCINNATI, OH

Award Year / Program / Phase: 2011 / SBIR / Phase II
Agency: HHS
Principal Investigator: Aniruddha Puntambekar – 513-429-2976
Award Amount: $997,254.00
Abstract:
Recent clinical research has established that this ratio is indicative of the activity of the CYP2A6 enzyme that metabolises nicotine. Nicotine is metabolized to COT and then to 3HC. People with high activity of this enzyme, clear nicotine faster and henceneed more nicotine to maintain the… More

IGF::OT::IGF OTHER FUNCTIONS SILOAM PHASE I, TOPIC 309, LOW VOLUME, ULTRA-SENSITIVE IMMUNODIAGNOSTIC SYSTEM

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Junhai Kai – 513-429-2976
Award Amount: $198,570.00
Abstract:
The goal of this SBIR project is to develop a low lost, ultrasensitive immunodiagnostic system for measuring multiple cancer biomarkers rapidly with small amount of samples. This system can be used by physicians to improve cancer early detection, diagnosis, prognosis and treatment monitoring. … More