This Small Business Innovation Research (SBIR) Phase I project aims to design, fabricate and test a novel Liquid Crystal on Silicon (LCOS) color display system that includes improved integrated pixel driver backplane integrated into a low cost, projection TV light engine. This LCOS display system… More

This Small Business Innovation Research (SBIR) Phase II project, matchbox projection systems, addresses a major opportunity in the multi-billion dollar projection display market. The main goal for the phase II project is to develop a Matchbox projector based on one liquid crystal on silicon (LCOS)… More

DESCRIPTION (provided by applicant) This Phase I Small Business Innovative Research application proposes to significantly advance optical coherence tomography (OCT) technology for imaging and detection of retinal pathologies by developing a novel swept source OCT (SS-OCT) system, which exhibits… More

DESCRIPTION (provided by applicant): Accurate in-vivo measurement of human corneal thickness (pachymetry) is an important diagnostic procedure in ophthalmology. Pachymetry is an important precursor to refractive surgery procedures such as LASIK, where the corneal thickness determines the appropriate… More

DESCRIPTION (provided by applicant): This Phase I Small Business Innovation Research (SB1R) application proposes to incorporate dramatic advances in optical coherence tomography (OCT) imaging technology into a microscope-based prototype for use in small animal imaging. This OCT microscope has the… More

DESCRIPTION (provided by applicant): This Phase II Small Business Innovation Research application will continue the development of the advanced OCT microscope system targeting applications in imaging small animals such as Drosophila, zebrafish, Xenopus, chick embryo and others. The result of the… More

Current data mining platforms generally consist of a collection of conventional processors that communicate with each other via a high-speed network (a cluster) or via shared memory (a symmetric multiprocessing system). As one adds more processors to either of these systems, the processing time… More

This Small Technology Transfer Research (STTR) Phase I research project will develop a novel liquid crystal polarization grating (LCPG) technology that operates on unpolarized light with strong potential to attain an unprecedented > 90% light diffraction efficiency. This will be the core technology… More

This Small Business Innovative Research (SBIR) Phase I project will develop a new instrument for the detection of early stage concern in human epithelial tissue based on a novel optical spectroscopic technique, Fourier-domain Low Coherence Interferometry (fLCl). Preliminary experiments with in… More

DESCRIPTION (provided by applicant): The objective of this research is to create a commercial prototype of a new optical biopsy system based on angle-resolved Low Coherence Interferometry (a/LIC). A/LCI is a novel optical technique that uses interferometr ic detection of elastically scattered light… More

This Small Business Innovation Research (SBIR) Phase I project develops a new method for preserving proteins by a Microglassification Process that controllably dehydrates proteins into microspheres. This process has the potential to stabilize proteins by removing water to a level that does not allow… More

This Phase I SBIR project intends to demonstrate the feasibility of a freshwater microbial community microarray called the WaterChipTM, for detecting the presence of an important model for mercury chemical pollutant in freshwater. By demonstrating its utility for detecting evidence of this… More

DESCRIPTION (provided by applicant): The overall objective of our Phase I and Phase II research and development effort is to achieve unprecedented preservation of monoclonal antibodies as diagnostics and therapeutics for human use. In Phase I we want to e xplore the utility of our recently… More

DESCRIPTION (provided by applicant): The objective of this Phase I SBIR project is to develop a system called Tummy-Time Motivator (TTM) that will be used to motivate children for postural control improvement. There is a clear relationship between the deve lopment of postural control and the amount… More

This Phase I Small Business Innovation Research project is to develop a novel, low cost, high performance and compact wavelength blocker for Reconfigurable Optical Add/Drop Multiplexer (ROADM) in fiber telecommunication networks. The primary benefit of an enterprise ROADM network is its ability to… More

This Small Business Innovation Research (SBIR) Phase II project will advance the recent discovery of an ambient temperature dehydration method ""Microglassification"" that is designed to more efficiently stabilize biomolecules for preservation. Lyophilization is the current process of choice, but it… More

DESCRIPTION (provided by applicant): The objective of this research is to create a clinical prototype of a new optical biopsy system based on angle-resolved low coherence interferometry (a/LCI). a/LCI is a novel optical technique that uses interferometric detection of elastically scattered light to… More

DESCRIPTION (provided by applicant): The worldwide market for implant-based dental reconstruction products will approach nearly 3.5 billion by 2010 with an annual growth rate of 15%. Currently, an implant patient waits 3-14 months from the time of tooth e xtraction until a functioning crown is in… More

DESCRIPTION (provided by applicant): The goal of this small business innovation research (SBIR) grant is to develop novel compounds that can significantly improve the effectiveness of Type-II diabetes treatment. The need for anti-diabetic drugs is enormouswith over 23 million American diabetics and… More

DESCRIPTION (provided by applicant): Invasive aspergillosis (IA) caused by the fungus Aspergillus fumigatus is the most frequent fungal cause of death in immunocompromised patients. The number of patients at risk for developing IA is steadily increasing due to advances in medicine. Early and… More

DESCRIPTION (provided by applicant): This Phase I Small Business Innovation Research (SBIR) proposal seeks to develop an innovative, inexpensive, and reliable system, called the Tummy-Time Motivator (TTM), to motivate children to improve postural control.Postural control is the foundation for the… More

DESCRIPTION (provided by applicant): The objective of this Phase I SBIR application is the proof-of-principle for an innovative and reliable subdermal electroencephalogram (EEG) monitor. The EEG is the most widely-used monitor of brain function. Over a fifth of the population suffers from brain… More