USA flag logo/image

An Official Website of the United States Government

Cassette Based Robotic Multiple Cell Culture System

Award Information

Agency:
National Aeronautics and Space Administration
Branch:
N/A
Award ID:
56427
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
012278
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
TECHSHOT, INC.
7200 Highway 150 GREENVILLE, IN 47124-9515
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2002
Title: Cassette Based Robotic Multiple Cell Culture System
Agency: NASA
Contract: NAS9-02081
Award Amount: $69,899.00
 

Abstract:

The specific innovation proposed for continued research is a family of fully-automated (robotic) cell-culture systems, each a laboratory in a cassette, named collectively ?Multicult?. SHOT will incorporate several technical innovations, including options for gentle mixing of cell suspensions, transparent monolayer culture surfaces, control of inertial load (?g-level?) by rotation within the cassette, pH monitoring, adding fresh medium or fixatives with immediate mixing, and real-time imaging of cells in transparent containers. SHOT will perform research leading to (1) a cassette-based rotating plate for exposing 8 cultures of suspended cells to acceleration levels from 1 to 5 g while facilitating fluid additions and balancing out all forces other than centrifugal and gravity vectors, (2) a curved-wall transparent culture vessel for centrifugal studies of adherent cells, (3) a miniaturized non-invasive pH reader, (4) a compact video microscope, (5) a control-and-data network of embedded processors, and (6) a deliverable prototype cassette-based Multicult system incorporating these features for the sponsor. SHOT will use the results of this research to develop, in addition to a cell culture capability for space flight, marketable instruments based on its pH reader, centrifugal culture plates and autonomously controlled Multicults.

Principal Investigator:

Dr Paul Todd
Chief Scientist
8129239591
ptodd@shot.com

Business Contact:

Mark S. Deuser
President & CEO
8129239591
mdeuser@shot.com
Small Business Information at Submission:

Space Hardware Optimization Technology
7200 Highway 150 Greenville, IN 47124

EIN/Tax ID: 351784668
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No