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Company Information:

Company Name:
Sphinx Pharmaceuticals
Address:
Box 52330, 4 University Place
Durham, NC 27717
Phone:
N/A
URL:
N/A
EIN:
N/A
DUNS:
N/A
Number of Employees:
N/A
Woman-Owned?:
No
Minority-Owned?:
No
HUBZone-Owned?:
No

Commercialization:

Has been acquired/merged with?:
N/A
Has had Spin-off?:
N/A
Has Had IPO?:
N/A
Year of IPO:
N/A
Has Patents?:
N/A
Number of Patents:
N/A
Total Sales to Date $:
$ 0.00
Total Investment to Date $
$ 0.00
POC Title:
N/A
POC Name:
N/A
POC Phone:
N/A
POC Email:
N/A
Narrative:
N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $225,000.00 4

Award List:

PROTEIN KINASE C THERAPEUTIC DEVELOPMENTAL TOOLS

Award Year / Program / Phase:
1987 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Carson r loomis
Abstract:
The long-term goals of this research are to contribute to anunderstanding of the role of protein kinase c in neoplastic transformation and cellular regulation by signal transduction processes. protein kinase c functions to transduce sn-1,2-diacylglycerol second messengers, produced in response to… More

CYCLIC AMP BINDING PROTEINS AND RAS FUNCTION

Award Year / Program / Phase:
1992 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Men-hwei Tsai
Abstract:
Two camp binding proteins (50k and 10k daltons) that alter biochemical properties of protoon- cogene ras in a camp dependent manner were isolated from bovine brain. in the presence of camp, the 50k dalton protein (p50) inhibited the nucleotide exchange of ras, whereas the 10k protein (p10) inhibited… More

MEMBRANE-BOUND RAD P21 REGULATION BY GAP AND LIPIDS

Award Year / Program / Phase:
1992 / SBIR / Phase I
Award Amount:
$50,000.00
Agency:
HHS
Principal Investigator:
Stephen B Bocckino
Abstract:
The long-term goal of this project is to discover drugs that will protect normal cells from cancer chemotherapy. the oncogene ras is present in approximately 30% of human tumors; a normal non-oncogenic ras is found in normal cells. this normal ras (but not oncogenic ras) can be switched off by the… More

Protein Kinase C Modulators from Marine Invertebrates

Award Year / Program / Phase:
1994 / SBIR / Phase I
Award Amount:
$75,000.00
Agency:
HHS
Principal Investigator:
Palaniappan Kulanthaivel
Abstract:
Discovery of new drugs depends largely upon random screening directed towards specificenzyme targets. Protein kinase C (PKC), a family of serine/threonine-specific protein kinases, is criticalin the control of multiple cellular responses, including gene expression, proliferation, differentiation… More