Often sample sizes for randomized clinical trials (rct) are too small because prior estimates of design parameters are inaccurate. therefore, a computerized approach to increasing sample size during a rct without increasing ai-level has important commercial application for organizations that perform… More

Because many randomized clinical trials (RCTs) study several important outcome variables thatmay respond to treatment, evaluation of efficacy is often difficult. Objective algorithms that combineinformation from all relevant variables may not capture satisfactorily the total experience of… More