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DEVELOPMEN OF A NEW DNA SEQUENCING INSTRUMENT

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
11261
Program Year/Program:
1989 / SBIR
Agency Tracking Number:
11261
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Sybtrel Biotechnology
1500 Edwards Avenue, Suite Q Harahan, LA 70123
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1989
Title: DEVELOPMEN OF A NEW DNA SEQUENCING INSTRUMENT
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP A DNA SEQUENCING INSTRUMENT UTILIZING THE PYROPHOSPHATE-BASED METHOD OF DNA SEQUENCING. THIS IS A NEW METHOD THAT DOES NOT USE ELECTROPHORESIS, RADIOACTIVITY, OR FLUORESCENCE. THE METHOD WORKS BY MEASURING PYROPHOSPHATE GENERATED BY THE DNA POLYMERIZATION REACTION. THE PYROPHOSPHATE IS MEASURED CONTINUOUSLY BY A DEVICE CONSISTING OF A SERIES OF COLUMNS CONTAINING ENZYMES COVALENTLY ATTACHED TO A SOLIDSUPPORT. PHASE I WILL BE DEVOTED TO SOLVING THE REMAINING BIOCHEMICAL PROBLEMS ASSOCIATED WITH THE METHOD. IF THE METHOD IS DEMONSTRATED TO WORK WELL ENOUGH, PHASE II WILL CONSIST OF CONSTRUCTION OF A PROTOTYPE INSTRUMENT SUITABLE FOR LARGE-SCALE PRODUCTION.

Principal Investigator:


0

Business Contact:

Small Business Information at Submission:

Sybtrel Biotechnology
3330 Causeway Blvd #433 Matairie, LA 70002

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No