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Development of a Neural Co-Culture Bioactive Compound Sensor

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
78065
Program Year/Program:
2006 / STTR
Agency Tracking Number:
A064-013-0249
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Synkera Technologies, Inc.
2605 Trade Centre Ave. LONGMONT, CO -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2006
Title: Development of a Neural Co-Culture Bioactive Compound Sensor
Agency / Branch: DOD / ARMY
Contract: W911NF-06-C-0093
Award Amount: $99,999.00
 

Abstract:

Synkera Technologies proposes to develop a bipartite Living Neural Networks (LNN) platform capable of sustaining two different types of intercommunicating neuronal modules that can be independently exposed to and record electrical and biochemical perturbations. The focal point of the proposed sensor will be a micromachined biochip platform for guided and reproducible growth of LNN on ceramic substrates. The advantages of this platform include the following: (1) improved growth characteristics of the neural co-culture, (2) the ability to reproducibly control neuronal and axonal outgrowth between two LNN, (3) the ability to provide discrete access of biochemical perturbations to each LNN, (4) the ability to provide nanoelectrode access with superior electrical characteristics and contact to the LNN, and (5) fewer processing steps for less expensive devices.

Principal Investigator:

Elizabeth Mirowski
7204948401
emirowski@synkera.com

Business Contact:

Stephen S. Williams
President and CTO
7204948401
swilliams@synkera.com
Small Business Information at Submission:

SYNKERA TECHNOLOGIES, INC.
2021 Miller Dr. Longmont, CO 80501

EIN/Tax ID: 364528660
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
UNIV. OF COLORADO
Office of Contracts and Grants
Boulder, CO 80309
Contact: Randall W. Draper
Contact Phone: (303) 492-2695
RI Type: Nonprofit college or university