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CARCINOGENESIS INFORMATION FOR ENVIRONMENTAL SUBSTANCES

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4907
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
4907
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Technical Database Services In
10 Columbus Cir #2300 New York, NY 10019
View profile »
Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1987
Title: CARCINOGENESIS INFORMATION FOR ENVIRONMENTAL SUBSTANCES
Agency: HHS
Contract: N/A
Award Amount: $264,000.00
 

Abstract:

THE OBJECTIVE OF PHASE I RESEARCH IS TO ESTABLISH THE CARCINOGENESIS INFORMATION DATABASE ENVIRONMENTAL SUBSTANCES(CIDES) AS A PROTOTYPE DATABASE CONTAINING NUMERICAL PROPERTIES DATA FOR ENVIRONMENTAL SUBSTANCES WHICH ARE KNOWNOR THOUGHT TO HAVE CARCINOGENIC PROPERTIES. THE GOAL WILL BE TO PRODUCE A DATABASE WHICH INCLUDES PHYSICAL-CHEMICAL PROPERTY DATA, BOTH POSITIVE AND NEGATIVE SHORT-TERM TEST RESULTS, AND HUMAN AND ANIMAL CARCINOGENESIS DATA. A UNIQUEAIM OF THIS RESEARCH PLAN IS TO APPLY OBJECTIVE CRITERIA TO THE EXPERIMENTAL STUDIES AND DATA IN THE DATABASE IN ORDER TO DERIVE A PAIR OF NUMBERS WHICH RATE: (1) THE PROBABILITYTHAT THE SUBSTANCE IS A CARCINOGEN, AND (2) THE RELIABILITY OF THE TEST RESULTS ON WHICH THAT PROBABILITY IS BASED. THESE TWO RATINGS WILL BE COMBINED INTO A CARCINOGENICITY RATIO WHICH WILL BE APPLIED TO EACH FACTOR. IN ADDITION, EACH PHYSICAL-CHEMICAL DATAPOINT WILL BE CODED WITH A QUALITY INDICATOR WHERE POSSIBLE. RESULTS OF THE PHASE I EFFORT WILL PROVIDE THE BASIS FOR COMPILING AND IMPLEMENTINGAN EVALUATED DATABASE FOR OVER 1000 KNOWN AND POTENTIAL CARCINOGENS DURING PHASE II. THE DATABASE AND ITS ASSOCIA- TED SOFTWARE WILL BE SUITABLE FOR ONLINE SEARCH AND RETRIEVAL AND AS MACHINE-READABLE PRODUCTS FOR RESEARCHERS INTO ONCOLOGIC EFFECTS.

Principal Investigator:

Mildred R Green
Principal Investigator
2122450044

Business Contact:

Small Business Information at Submission:

Technical Database Services In
10 Columbus Circle Suite 2300 New York, NY 10019

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No