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SBIR Phase II:Sensitive, Rapid Heterogeneous Immunoassays Based on Surface…

Award Information

National Science Foundation
Award ID:
Program Year/Program:
2010 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Concurrent Analytical, Inc.
150 Hamakua Dr. PMB 702 Kailua, HI 96734 2825
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: Yes
Phase 2
Fiscal Year: 2010
Title: SBIR Phase II:Sensitive, Rapid Heterogeneous Immunoassays Based on Surface Enhanced Raman Scattering and Gold Nanoparticle Labels
Agency: NSF
Contract: 1026890
Award Amount: $381,132.00


This Small Business Innovation Research (SBIR) Phase II project continues the development of an innovative diagnostic technology based on surface-enhanced Raman scattering (SERS) through its combination with gold nanoparticle labels, high-speed fluid handling, and sandwich-based immunoassays. This project, which builds on the successes of the SBIR Phase I effort, reflects a clear market need for high-speed, low-cost testing capable of providing rapid results commensurate with clinical diagnostic demands. As a market-entry point, the overarching goal is to create an extensible, multiplexed diagnostics platform for the causative agents of herpes: herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2). Herpes has reached near pandemic levels in the United States and other countries around the world. The development of such a detection platform would have clear utility across the diagnostics marketplace, from the physician's office and in-hospital POC to third-party clinical diagnostic laboratories, as a multiplexed platform for sexually transmitted diseases and beyond. The broader impacts of this research are realized with the development of a technique capable of providing absolute quantitation of HSV and many other viral diseases. Such a diagnostic tool would find a niche in large clinical laboratories, in research laboratories evaluating the antiviral efficacy of candidate vaccines, and with pathologists for defining infective pathogen thresholds, setting the stage for this technology to emerge as one of the premier tools in an arsenal of diagnostic technologies.

Principal Investigator:

Christian L. Schoen

Business Contact:

Christian L. Schoen
Small Business Information at Submission:

150 Hamakua Dr. PMB 702 Kailua, HI 96734

EIN/Tax ID: 421538908
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No