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MOLECULAR MIMICRY AFFINITY CHROMATOGRAPHY

Award Information

Agency:
Department of Energy
Branch:
N/A
Award ID:
7712
Program Year/Program:
1988 / SBIR
Agency Tracking Number:
7712
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Terrapin Diagnostics Inc.
165 Eighth Street #306 San Francisco, CA 94103
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1988
Title: MOLECULAR MIMICRY AFFINITY CHROMATOGRAPHY
Agency: DOE
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

SUPERIOR SEPARATION COLUMNS ARE BEING DEVELOPED IN THIS PROJECT TO BE USED WITH HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) SYSTEMS TO DETECT ENVIRONMENTAL TOXINSSUCH AS DDT. THE SEPARATION AND ANALYSIS OF COMPOUNDS BY HPLC SYSTEMS DEPENDS ON THE AMPLIFICATION OF SMALL DIFFERENCES IN THE RELATIVE AFFINITY OF THE COMPOUNDS BETWEEN THE COLUMN MATRIX AND THE SOLVENT. USING A FEW STANDARDIZED COLUMN MATRICES, CURRENT HPLC PROCEDURES REQUIRE ADJUSTMENT OF SOLVENT COMPOSITION TO PROVIDE ADEQUATE SEPARATION OF THE COMPOUNDS. BY CONTRAST, THE CURRENT WORK WILL OPTIMIZE THE COLUMN FOR PREFERENTIAL BINDING OF THE TARGET ANALYTE BY ATTACHING SELECTED MEMBERS OF A NOVEL CLASS OF AFFINITY LIGANDS TO THE COLUMN MATRIX.

Principal Investigator:

Lawrence m kauvar
0

Business Contact:

Jerrold L Glick
3036231221
Small Business Information at Submission:

Terrapin Diagnostics Ltd
165 Eighth Street #306 San Francisco, CA 94103

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No